Plantain (Plantago L.) species as modulators of prostaglandin E2 and tromboxane A2 production in inflammation.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2020.113140
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE World-wild distributed plantains (genus Plantago L.) are extensively used in the traditional, but some of them are also accepted in the modern medicine. Wide range of usages is mainly connected to the inflammation… read more here.
Keywords: production; ursolic acid; txa2; inflammation ... See more keywords
New insights into cancer's exploitation of platelets
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.14624
Abstract: Decades of research have led to vast improvements in our understanding and management of malignancy. However, cancer remains a leading cause of death worldwide. A major obstacle in treating most solid tumor malignancies is not… read more here.
Keywords: txa2; metastasis; cox; cancer ... See more keywords
Aspirin suppresses hepatic glucagon signaling through decreasing production of thromboxane A2.
Sign Up to like & getrecommendations! Published in 2023 at "Endocrinology"
DOI: 10.1210/endocr/bqac217
Abstract: Excessive hepatic glucose production (HGP) is a major cause of fasting hyperglycemia in diabetes and antihyperglycemic therapy takes center stage. Nonsteroidal anti-inflammatory drugs (NSAIDs), such as acetylsalicylic acid(Aspirin), reduce hyperglycemia caused by unrestrained gluconeogenesis in… read more here.
Keywords: glucagon signaling; thromboxane; production; gluconeogenesis ... See more keywords
The Role and Regulation of Thromboxane A2 Signaling in Cancer-Trojan Horses and Misdirection
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27196234
Abstract: Over the last two decades, there has been an increasing awareness of the role of eicosanoids in the development and progression of several types of cancer, including breast, prostate, lung, and colorectal cancers. Several processes… read more here.
Keywords: role regulation; role; txa2 signaling; thromboxane ... See more keywords