LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "txnip nlrp3" as a keyword



Photo from wikipedia

Ferulic acid relieved ulcerative colitis by inhibiting the TXNIP/NLRP3 pathway in rats

Sign Up to like & get
recommendations! Published in 2022 at "Cell Biology International"

DOI: 10.1002/cbin.11935

Abstract: Ulcerative colitis (UC) is a disorder of the bowel that is characterized by a chronic inflammatory response. The traditional Chinese herbal medicine ferulic acid (FA) is known for its antioxidant, antiapoptotic, and antiinflammatory properties. However,… read more here.

Keywords: nlrp3 signaling; ulcerative colitis; pathway; txnip nlrp3 ... See more keywords
Photo by ktabori from unsplash

Salidroside alleviates high glucose-induced oxidative stress and extracellular matrix accumulation in rat glomerular mesangial cells by the TXNIP-NLRP3 inflammasome pathway.

Sign Up to like & get
recommendations! Published in 2017 at "Chemico-biological interactions"

DOI: 10.1016/j.cbi.2017.10.012

Abstract: Diabetic nephropathy (DN) is a metabolic disease characterized by mesangial cell proliferation and extracellular matrix (ECM) accumulation. Salidroside (SAL) is the major ingredient in Rhodiola rosea and possesses beneficial effects on DN. This study aimed… read more here.

Keywords: accumulation; sal; txnip nlrp3; nlrp3 inflammasome ... See more keywords
Photo by markusspiske from unsplash

Potential of Forsythoside I as a therapeutic approach for acute lung injury: Involvement of TXNIP/NLRP3 inflammasome.

Sign Up to like & get
recommendations! Published in 2021 at "Molecular immunology"

DOI: 10.1016/j.molimm.2021.03.004

Abstract: OBJECTIVE To explore the role of Forsythoside I (FI) in acute lung injury (ALI) mouse and its underling mechanism. METHODS The cell models of ALI are constructed by LPS induction. After pretreatment with different concentrations… read more here.

Keywords: lung injury; txnip nlrp3; txnip; acute lung ... See more keywords

Effects of Hypoxic Environment on Periodontal Tissue through the ROS/TXNIP/NLRP3 Inflammasome Pathway

Sign Up to like & get
recommendations! Published in 2022 at "BioMed Research International"

DOI: 10.1155/2022/7690960

Abstract: There is low evidence for the possible association between obstructive sleep apnea-hypopnea syndrome (OSAHS) and periodontitis, necessitating further research. This study was aimed at investigating this association. For the in vitro study, 8-day-old Wistar rats… read more here.

Keywords: expression; group; pathway; txnip nlrp3 ... See more keywords
Photo by tcwillmott from unsplash

Activation of LRP1 Ameliorates Cerebral Ischemia/Reperfusion Injury and Cognitive Decline by Suppressing Neuroinflammation and Oxidative Stress through TXNIP/NLRP3 Signaling Pathway in Mice

Sign Up to like & get
recommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/8729398

Abstract: Cerebral ischemia/reperfusion (I/R) injury is a clinical event associated with high morbidity and mortality. Neuroinflammation plays a crucial role in the pathogenesis of I/R-induced brain injury and cognitive decline. Low-density lipoprotein receptor-related protein-1 (LRP1) can… read more here.

Keywords: lrp1; txnip; signaling pathway; nlrp3 signaling ... See more keywords
Photo by art_almighty from unsplash

miR-17-5p Promotes Glucose Uptake of HTR8/SVneo Trophoblast Cells by Inhibiting TXNIP/NLRP3 Inflammasome Pathway

Sign Up to like & get
recommendations! Published in 2022 at "Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy"

DOI: 10.2147/dmso.s385774

Abstract: Introduction Gestational diabetes mellitus (GDM) is one of the common metabolic disorders of pregnancy and results in poor pregnancy outcomes for both mother and fetus. MiR-17-5p is considered as the strongest predictor of metabolic syndrome… read more here.

Keywords: mir; txnip; txnip nlrp3; htr8 svneo ... See more keywords
Photo from wikipedia

miRNA-141 Induced Pyroptosis in Intervertebral Disk Degeneration by Targeting ROS Generation and Activating TXNIP/NLRP3 Signaling in Nucleus Pulpous Cells

Sign Up to like & get
recommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2020.00871

Abstract: The role and mechanism of pyroptosis in intervertebral disk (IVD) degeneration are unclear. MicroRNAs (miRNAs) regulate the viability and function of nucleus pulposus cells (NPCs) in IVDs and are related to pyroptosis. We performed microarray… read more here.

Keywords: pyroptosis; degeneration; ros generation; txnip nlrp3 ... See more keywords
Photo by mertguller from unsplash

Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 Inflammasome Activity and Activating NRF2 Signaling

Sign Up to like & get
recommendations! Published in 2020 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2020.593368

Abstract: Multiple sclerosis (MS), an autoimmune and degenerative disease, is characterized by demyelination and chronic neuroinflammation. Bixin is a carotenoid isolated from the seeds of Bixa orellana that exhibits various potent pharmacological activities, including antioxidant, anti-inflammatory,… read more here.

Keywords: eae mice; bixin; autoimmune encephalomyelitis; txnip nlrp3 ... See more keywords
Photo by boxedwater from unsplash

N-Lobe of TXNIP Is Critical in the Allosteric Regulation of NLRP3 via TXNIP Binding

Sign Up to like & get
recommendations! Published in 2022 at "Frontiers in Aging Neuroscience"

DOI: 10.3389/fnagi.2022.893919

Abstract: Inflammasomes are cytoplasmic complexes that form in response to exogenous microbial invasions and endogenous damage signals. Among the known inflammasomes, the activation of the NACHT (NAIP, CIITA, HET-E, and TP1 domain), leucine-rich repeat, and pyrin… read more here.

Keywords: allosteric regulation; txnip; nlrp3 interaction; regulation nlrp3 ... See more keywords
Photo by rainierridao from unsplash

Tangshen Formula Attenuates Diabetic Kidney Injury by Imparting Anti-pyroptotic Effects via the TXNIP-NLRP3-GSDMD Axis

Sign Up to like & get
recommendations! Published in 2020 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2020.623489

Abstract: We previously reported that Tangshen formula (TSF), a Chinese herbal medicine for diabetic kidney disease (DKD) therapy, imparts renal protective effects. However, the underlying mechanisms of these effects remain unclear. Pyroptosis is a form of… read more here.

Keywords: txnip nlrp3; tangshen formula; gsdmd; nlrp3 inflammasome ... See more keywords

Chrysin ameliorates synovitis and fibrosis of osteoarthritic fibroblast-like synoviocytes in rats through PERK/TXNIP/NLRP3 signaling

Sign Up to like & get
recommendations! Published in 2023 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2023.1170243

Abstract: Objective: Synovitis and fibrosis are common pathological features of knee osteoarthritis (KOA). The interaction of synovitis and fibrosis can promote KOA progression. Chrysin (CHR), a natural flavonoid, may treat inflammation and prevent fibrosis. However, the… read more here.

Keywords: nlrp3 signaling; synovitis fibrosis; perk txnip; fibrosis ... See more keywords