Blocking CHOP-dependent TXNIP shuttling to mitochondria attenuates albuminuria and mitigates kidney injury in nephrotic syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2116505119
Abstract: Significance Albuminuria is the hallmark of nephrotic syndrome (NS), a leading cause of chronic kidney disease affecting 500 million people worldwide. Thus, there is a clear need to discover novel drug targets to treat proteinuric… read more here.
Keywords: txnip; nephrotic syndrome; txnip shuttling; shuttling mitochondria ... See more keywords