Combination Treatment with Orlistat-Containing Nanoparticles and Taxanes Is Synergistic and Enhances Microtubule Stability in Taxane-Resistant Prostate Cancer Cells
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DOI: 10.1158/1535-7163.mct-17-0013
Abstract: Taxane-based therapy provides a survival benefit in patients with metastatic prostate cancer, yet the median survival is less than 20 months in this setting due in part to taxane-associated resistance. Innovative strategies are required to… read more here.
Keywords: taxane; taxane resistant; prostate cancer; cancer ... See more keywords
The CCL2–CCR2 Axis Contributes to Migration of Cabazitaxel-resistant Prostate Cancer Cells
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DOI: 10.21873/anticanres.16423
Abstract: Background/Aim: Developing resistance to cabazitaxel is a major challenge in patients with docetaxel- and castration-resistant prostate cancer (CRPC) since it is frequently administered as a last resort. We have previously reported that CCL2 induces resistance… read more here.
Keywords: cabazitaxel; du145 txr; txr; txr cxr ... See more keywords