Structural insight into a novel indole prenyltransferase in hapalindole-type alkaloid biosynthesis.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.12.039
Abstract: FamD1 is a novel CloQ/NphB-family indole prenyltransferase which involves in hapalindole-type alkaloid biosynthesis. Here the native FamD1 structure and three protein-ligand complexes are analyzed to investigate the molecular basis of substrate binding and catalysis. FamD1… read more here.
Keywords: hapalindole type; indole prenyltransferase; type alkaloid; alkaloid biosynthesis ... See more keywords
A new diketopiperazine-type alkaloid from the endophytic fungus penicillium expansum.
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DOI: 10.1080/14786419.2022.2099391
Abstract: A chemical investigation on an endophytic fungus Penicillium expansum isolated from the medicinal plant Plantago depressa Willd. (Plantaginaceae) afforded one new diketopiperazine-type alkaloid, namely penicimine A (1), as well as two known congeners (2 and… read more here.
Keywords: type alkaloid; endophytic fungus; fungus penicillium; diketopiperazine type ... See more keywords
A new β-carboline-type alkaloid from the flowers of Calotropis gigantea (L.) W.T.Aiton.
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DOI: 10.1080/14786419.2023.2208259
Abstract: In our antioxidant screening of some Vietnamese plant extracts, the CHCl3-soluble fraction from Calotropis gigantea (L.) W.T.Aiton flowers showed moderate DPPH free radical scavenging activity with an IC50 value of 55.8 μg/mL. Thus, a further phytochemical… read more here.
Keywords: carboline type; new carboline; type alkaloid; calotropis gigantea ... See more keywords