Alopecines A-E, five chloro-containing matrine-type alkaloids with immunosuppressive activities from the seeds of Sophora alopecuroides.
Sign Up to like & getrecommendations! Published in 2020 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2020.103812
Abstract: Alopecines A-E (1-5), five unusual matrine-type alkaloids featuring with an additional dichlorocyclopropane (1-3) or a di/tri-chloromethyl (4/5) attached on the D ring, were isolated from the seeds of Sophora alopecuroides. Their structures and absolute configurations… read more here.
Keywords: type alkaloids; seeds sophora; matrine type; sophora alopecuroides ... See more keywords
Trimeric and dimeric Aspidosperma-type alkaloids from leaves of Tabernaemontana divaricata 'Dwaft'.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.105314
Abstract: Continued interest in bioactive monoterpenoid indole alkaloids and the purpose to explore the artificial cultivation influence on the chemical composition in the same plant species, 8 undescribed Aspidosperma-type alkaloids including two unprecedented trimers, taberdivarines A-B… read more here.
Keywords: type alkaloids; tabernaemontana divaricata; leaves tabernaemontana; aspidosperma type ... See more keywords
Lycodine-type alkaloids from Lycopodiastrum casuarinoides and their cholinesterase inhibitory activities.
Sign Up to like & getrecommendations! Published in 2018 at "Fitoterapia"
DOI: 10.1016/j.fitote.2018.09.005
Abstract: Four new trace alkaloids with lycodine-related structures, Lycocasuarinines A-D (1-4), together with seven known analogues (5-11), were isolated from the chloroform extract of Lycopodiastrum casuarinoides. The structures and stereochemistry of 1-4 were elucidated by spectroscopic… read more here.
Keywords: type alkaloids; lycopodiastrum casuarinoides; alkaloids lycopodiastrum; inhibitory activities ... See more keywords
Monoterpene indole alkaloids with diverse skeletons from the stems of Rauvolfia vomitoria and their acetylcholinesterase inhibitory activities.
Sign Up to like & getrecommendations! Published in 2020 at "Phytochemistry"
DOI: 10.1016/j.phytochem.2020.112450
Abstract: Nine undescribed monoterpene indole alkaloids, rauvomitorine A-I, including an unprecedented C-9-methoxymethylene-sarpagine framework alkaloid, two rare suaveoline framework type alkaloids, and six yohimbine framework type alkaloids, as well as eleven known alkaloids, were isolated from the… read more here.
Keywords: type alkaloids; framework; monoterpene indole; inhibitory activities ... See more keywords
Iboga-type alkaloids with Indolizidino[8,7-b]Indole scaffold and bisindole alkaloids from Tabernaemontana bufalina Lour.
Sign Up to like & getrecommendations! Published in 2022 at "Phytochemistry"
DOI: 10.1016/j.phytochem.2022.113089
Abstract: Phytochemical investigation on the aerial parts of Tabernaemontana bufalina Lour. (Apocynaceae) led to the identification of four undescribed monoterpenoid indole alkaloids named taberbufamines A-D, an undescribed natural product, and fourteen known indole alkaloids. The structures… read more here.
Keywords: bufalina lour; tabernaemontana bufalina; iboga type; indolizidino indole ... See more keywords
Matrine-Type Alkaloids with Anti-Tomato Spotted Wilt Virus Activity from the Root of Sophora tonkinensis Gagnep.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c09003
Abstract: As a continuation of our research on the development of pesticide active quinolizidine alkaloids (QAs) from the family Fabaceae, the chemical constituents of the root of Sophora tonkinensis Gagnep. were systematically investigated. Seventeen new matrine-type… read more here.
Keywords: tonkinensis gagnep; tonkinensis; matrine type; type alkaloids ... See more keywords
Diketopiperazine-Type Alkaloids from a Deep-Sea-Derived Aspergillus puniceus Fungus and Their Effects on Liver X Receptor α.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.9b00055
Abstract: Eight new diketopiperazine-type alkaloids including four oxepin-containing diketopiperazine-type alkaloids, oxepinamides H-K (1-4), and four 4-quinazolinone alkaloids, puniceloids A-D (5-8), together with two known analogues (9 and 10), were isolated from the culture broth extracts of… read more here.
Keywords: type alkaloids; deep sea; aspergillus puniceus; sea derived ... See more keywords
Unified Total Synthesis of Stemoamide-Type Alkaloids by Chemoselective Assembly of Five-Membered Building Blocks.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b10944
Abstract: A unified total synthesis of stemoamide-type alkaloids is reported. Our synthetic approach features the chemoselective convergent assembly of five-membered building blocks via stemoamide as the common precursor to tetracyclic natural products. The synthesis consists of… read more here.
Keywords: stemoamide; type alkaloids; synthesis stemoamide; stemoamide type ... See more keywords
Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-23611-0
Abstract: Chinese goldthread (Coptis chinensis Franch.), a member of the Ranunculales, represents an important early-diverging eudicot lineage with diverse medicinal applications. Here, we present a high-quality chromosome-scale genome assembly and annotation of C. chinensis. Phylogenetic and… read more here.
Keywords: type alkaloids; protoberberine type; coptis chinensis; chinensis ... See more keywords
Antimicrobial crinane-type alkaloids from the bulbs of Crinum latifolium.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Asian natural products research"
DOI: 10.1080/10286020.2020.1831479
Abstract: A phytochemical investigation on the 90% ethanol aqueous extract of the bulbs of Crinum latifolium led to the isolation of three new crinane-type alkaloids, designated as crinumlatines A-C (1-3). The structures of the new compounds… read more here.
Keywords: crinane type; type alkaloids; crinum latifolium; bulbs crinum ... See more keywords
Two new cytisine-type alkaloids from the seeds of Thermopsis lanceolata
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Asian Natural Products Research"
DOI: 10.1080/10286020.2021.2020759
Abstract: Abstract Two new (1 and 2) cytisine-type alkaloids that were chemically inseparable isomers (present in a 1:1 ratio) were identified from the seeds of Thermopsis lanceolata R. Br. Their structures were elucidated by comprehensive spectroscopic… read more here.
Keywords: new cytisine; thermopsis lanceolata; seeds thermopsis; two new ... See more keywords