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Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17600
Abstract: The dysfunction of type II alveolar epithelial cells (AECIIs), mainly manifested by apoptosis, has emerged as a major component of idiopathic pulmonary fibrosis (IPF) pathophysiology. A pivotal mechanism leading to AECIIs apoptosis is mitochondrial dysfunction.…
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Keywords:
apoptosis;
lung fibrosis;
epithelial cells;
alveolar epithelial ... See more keywords
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Published in 2021 at "Journal of International Medical Research"
DOI: 10.1177/0300060520986049
Abstract: Objective The primary aim of our study was to explore the mechanisms through which long non-coding RNA (lncRNA)-mediated sirtuin-1 (SIRT1) signaling regulates type II alveolar epithelial cell (AECII) senescence induced by a cigarette smoke-media suspension…
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Keywords:
senescence;
long non;
non coding;
coding rna ... See more keywords
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Published in 2022 at "Allergologia et immunopathologia"
DOI: 10.15586/aei.v50i5.632
Abstract: BACKGROUND The development of acute lung injury (ALI) into a severe stage leads to acute respiratory distress syndrome (ARDS). The morbidity and mortality of ALI and ARDS are very high. Objective: This study is aimed…
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Keywords:
klf6;
apoptosis;
lps induced;
alveolar epithelial ... See more keywords
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1
Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.854250
Abstract: Understanding the signaling pathway regulatory mechanisms in type II alveolar epithelial (ATII) cells, the progenitor cells responsible for proliferating and regenerating type I alveolar epithelial (ATI) and ATII cells, in Tibetan pigs is beneficial for…
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Keywords:
cells tibetan;
tibetan pigs;
alveolar epithelial;
atii cells ... See more keywords
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1
Published in 2020 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2020.00452
Abstract: Background: Transdifferentiation of type II alveolar epithelial cells (AECII) into type I alveolar epithelial cells (AECI) is involved in neonatal respiratory distress syndrome (NRDS). Different ligands of the Notch pathway could have different effects on…
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Keywords:
epithelial cells;
transdifferentiation;
group;
proliferation ... See more keywords
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2
Published in 2022 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.64285
Abstract: The lamellar body (LB), a concentric structure loaded with surfactant proteins and phospholipids, is an organelle specific to type 2 alveolar epithelial cells (AT2). However, the origin of LBs has not been fully elucidated. We…
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Keywords:
alveolar epithelial;
lamellar body;
production;
type ... See more keywords