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Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-73356-1
Abstract: Single-cell RNA sequencing (scRNA-seq) is a key technology for investigating cell development and analysing cell diversity across various diseases. However, the high dimensionality and extreme sparsity of scRNA-seq data pose great challenges for accurate cell…
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Keywords:
type annotation;
attention;
cell;
model ... See more keywords
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Published in 2025 at "Communications Biology"
DOI: 10.1038/s42003-025-08745-x
Abstract: Ensuring accurate cell type annotation in single-cell RNA sequencing data is a significant challenge, as both expert and automated methods can be biased or constrained by their training data, leading to errors and time-consuming revisions.…
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Keywords:
type annotation;
language;
cell;
model ... See more keywords
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Published in 2023 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbad179
Abstract: Undoubtedly, single-cell RNA sequencing (scRNA-seq) has changed the research landscape by providing insights into heterogeneous, complex and rare cell populations. Given that more such data sets will become available in the near future, their accurate…
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Keywords:
cell;
type annotation;
data sets;
cell type ... See more keywords
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Published in 2023 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbad195
Abstract: Single-cell omics technologies have made it possible to analyze the individual cells within a biological sample, providing a more detailed understanding of biological systems. Accurately determining the cell type of each cell is a crucial…
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Keywords:
cell;
single cell;
type annotation;
cell type ... See more keywords
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1
Published in 2021 at "Nucleic acids research"
DOI: 10.1093/nar/gkab775
Abstract: Advances in single-cell RNA sequencing (scRNA-seq) have furthered the simultaneous classification of thousands of cells in a single assay based on transcriptome profiling. In most analysis protocols, single-cell type annotation relies on marker genes or…
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Keywords:
single cell;
cell;
type annotation;
scdeepsort ... See more keywords
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1
Published in 2022 at "Communications Biology"
DOI: 10.1101/2022.06.22.497193
Abstract: Cell type annotation is critical to understand the cell population heterogeneity in the single-cell RNA sequencing (scRNA-seq) analysis. Due to their fast, precise, and user-friendly advantages, automatic annotation methods are gradually replacing traditional unsupervised clustering…
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Keywords:
cell;
type annotation;
rare cell;
scbalance ... See more keywords
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Published in 2020 at "BMC Genomics"
DOI: 10.1186/s12864-020-07223-4
Abstract: Background Current single cell analysis methods annotate cell types at cluster-level rather than ideally at single cell level. Multiple exchangeable clustering methods and many tunable parameters have a substantial impact on the clustering outcome, often…
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Keywords:
single cell;
type annotation;
cell;
cell type ... See more keywords
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Published in 2025 at "BMC Biology"
DOI: 10.1186/s12915-025-02128-8
Abstract: Recent advancements in single-cell RNA sequencing have greatly expanded our knowledge of the heterogeneous nature of tissues. However, robust and accurate cell type annotation continues to be a major challenge, hindered by issues such as…
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Keywords:
consensus;
type annotation;
cell;
gene ... See more keywords
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Published in 2025 at "PLOS Computational Biology"
DOI: 10.1371/journal.pcbi.1012904
Abstract: Cell type annotation is crucial in single-cell RNA sequencing data analysis because it enables significant biological discoveries and deepens our understanding of tissue biology. Given the high-dimensional and highly sparse nature of single-cell RNA sequencing…
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Keywords:
type annotation;
single cell;
biology;
cell ... See more keywords
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Published in 2025 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2025.1553352
Abstract: Single-cell RNA sequencing (scRNA-seq) has emerged as a powerful tool for understanding cellular heterogeneity, providing unprecedented resolution in molecular regulation analysis. Existing supervised learning approaches for cell type annotation primarily utilize gene expression profiles from…
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Keywords:
type annotation;
cell;
network;
scrna seq ... See more keywords
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Published in 2023 at "Frontiers in Psychology"
DOI: 10.3389/fpsyg.2022.1075932
Abstract: Dictation is considered an efficient exercise for testing the language proficiency of learners of French as a Foreign Language (FFL). However, the traditional teaching approach to dictation reduces the instructional feedback efficiency. To remedy this,…
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Keywords:
dictation;
error;
type annotation;
error type ... See more keywords