Cobalt Bromide-Catalyzed Negishi-Type Cross-Coupling of Amides.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00940
Abstract: Herein, we describe a novel Negishi-type cross-coupling of amides employing only cobalt bromide salt as the catalyst. This original reaction is highly tolerant to various glutarimide amides as well as organozinc coupling partners. These conditions… read more here.
Keywords: type cross; coupling amides; cobalt bromide; negishi type ... See more keywords
Pd-catalyzed Suzuki-type cross-coupling of 2-pyridyl carbamoyl fluorides.
Sign Up to like & getrecommendations! Published in 2024 at "Chemical communications"
DOI: 10.1039/d4cc02431a
Abstract: We describe a palladium-catalyzed Suzuki-type cross-coupling reaction of 2-pyridyl carbamoyl fluorides with boronic acids, which provides entry to medicinally relevant pyridyl amides. Mechanistic studies, including the synthesis and reactivity of carbamoyl Pd-F complexes, reveal the… read more here.
Keywords: cross coupling; type cross; catalyzed suzuki; pyridyl carbamoyl ... See more keywords