Immunomodulatory activities of sulfated Cyclocarya paliurus polysaccharides with different degrees of substitution on mouse spleen lymphocytes
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2019.103706
Abstract: Abstract Two sulfated polysaccharides SCP3 and SCP5 with degree of substitution (DS) 0.45 and 0.13 were obtained by modifying the Cyclocarya paliurus polysaccharide (CP) with chlorosulfonic acid-pyridine method. Results demonstrated that the physicochemical properties, molar… read more here.
Keywords: type cytokines; immunomodulatory activities; sulfated polysaccharides; cyclocarya paliurus ... See more keywords
Advancing precision medicine for asthma by focusing on type 2 cytokines and alarmins.
Sign Up to like & getrecommendations! Published in 2025 at "Current opinion in allergy and clinical immunology"
DOI: 10.1097/aci.0000000000001081
Abstract: PURPOSE OF REVIEW Asthma is a heterogeneous disease encompassing distinct phenotypes and endotypes. Advances in elucidating the pathogenic role of type 2 (T2) cytokines and epithelial-derived alarmins have profoundly reshaped our understanding of airway inflammation… read more here.
Keywords: cytokines alarmins; medicine; medicine asthma; type cytokines ... See more keywords
Possible Involvement of Type 2 Cytokines in Alloknesis in Mouse Models of Menopause and Dry Skin.
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DOI: 10.1111/exd.14422
Abstract: Alloknesis, an abnormal itch sensation induced by innocuous stimuli, is a key phenomenon in the vicious itch-scratch cycle in patients with atopic dermatitis. Dry skin and pruritus, including alloknesis, are major health problems in peri-… read more here.
Keywords: type cytokines; dry skin; alloknesis; mice ... See more keywords
ILC2 Diversity, Location, and Function in Pulmonary Disease
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DOI: 10.1111/imr.70036
Abstract: Type‐2 inflammation is driven by the production of canonical type‐2 cytokines IL‐4, IL‐5, and IL‐13. Type‐2 cytokines promote mucus production, innate immune cell recruitment, and smooth muscle contractility in mucosal tissues. These hallmarks of type‐2… read more here.
Keywords: disease; location function; ilc2 diversity; pulmonary disease ... See more keywords
Abstract A085: Elucidating the Crosstalk between Cancer Associated Fibroblasts and the T Regulatory/T Helper 2 Axis in Pancreas Cancer
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.pancreatic25-a085
Abstract: Pancreatic ductal adenocarcinoma (PDA) is a dismal disease with a 5-year survival rate of only 13%. A hallmark feature of this disease is its abundant microenvironment that consists of dense fibrotic stroma and immune cells… read more here.
Keywords: cancer; elucidating crosstalk; crosstalk cancer; pda ... See more keywords
Type-1 cytokines regulate matrix metalloprotease-9 production and E-cadherin disruption to promote melanocyte loss in vitiligo.
Sign Up to like & getrecommendations! Published in 2020 at "JCI insight"
DOI: 10.1172/jci.insight.133772
Abstract: Loss of melanocytes is the pathological hallmark of vitiligo, a chronic inflammatory skin depigmenting disorder induced by exaggerated immune response, including autoreactive CD8 T cells producing high levels of type-1 cytokines. However, the interplay between… read more here.
Keywords: type cytokines; vitiligo; disruption; skin ... See more keywords
Streptococcus agalactiae-induced blistering distal dactylitis diagnosed by DNA analysis
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Dermatology"
DOI: 10.1684/ejd.2022.4338
Abstract: (842 pg/mL and 1,356 pg/mL, respectively). The patient showed good compliance with 4 mg/day baricitinib treatment, without any relapse or adverse events. The EASI score remained 5 until 52 weeks, and DLQI, P-NRS, and ADCT… read more here.
Keywords: non type; agalactiae induced; jak inhibitors; type cytokines ... See more keywords
Sarcodia suiae Water Extract Promotes the Expression of Proinflammatory and Th1-Type Cytokines and Delay the Onset of Mortality in Cobia (Rachycentron canadum) During Photobacterium damselae subsp. damselae Infection
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.801501
Abstract: Cobia (Rachycentron canadum) is a marine fish of high economic value that grows at a fast rate. However, intensive fish farming has led to disease outbreaks in cobia cultures, which is highly costly to the… read more here.
Keywords: phdd; th1 type; damselae; cobia ... See more keywords
Hepatic iNKT cells produce type 2 cytokines and restrain antiviral T cells during acute hepacivirus infection
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.953151
Abstract: Chronic hepatitis C virus (HCV) infection is a curable disease, but the absence of a vaccine remains a major problem in infection prevention. The lack of small animal models and limited access to human liver… read more here.
Keywords: type cytokines; antiviral cells; infection; inkt cells ... See more keywords