Tagalide A and tagalol A, naturally occurring 5/6/6/6- and 5/6/6-fused cyclic dolabrane-type diterpenes: a new insight into the anti-breast cancer activity of the dolabrane scaffold
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DOI: 10.1039/c8qo00010g
Abstract: Tagalide A (1) and tagalol A (2), representing dolabrane-type diterpenes with unprecedented ring-A/B/C/D- and ring-A/B/C-fused cores (vii–viii), respectively, were isolated from the Chinese mangrove, Ceriops tagal. The relative and absolute configurations of these dolabranes were… read more here.
Keywords: type diterpenes; breast cancer; dolabrane type; dolabrane ... See more keywords
Cassane-type diterpenes from Caesalpinia minax induce apoptosis in pituitary adenoma: structure–activity relationship, ER stress and Wnt/β-catenin pathways
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DOI: 10.1080/10286020.2016.1217520
Abstract: Abstract Plant-derived natural products have been the highly significant sources of novel antitumor agents. The cassane-type diterpenes of genus Caesalpinia have been reported to bear antiproliferative activities toward different types of cancer cells. In this… read more here.
Keywords: structure activity; activity relationship; type diterpenes; cassane type ... See more keywords
New ingol-type diterpenes from the latex of Euphorbia resinifera
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DOI: 10.1080/10286020.2018.1498084
Abstract: Abstract Two new ingol-type diterpenes, euphoresins A–B (1–2), have been isolated from the methanol extract of Euphorbium, the latex of Euphorbia resinifera Berg. Their structures were established on the basis of extensive analyses of their… read more here.
Keywords: type diterpenes; latex euphorbia; diterpenes latex; new ingol ... See more keywords
Cytotoxic pimarane-type diterpenes from the marine sediment-derived fungus Eutypella sp. FS46
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DOI: 10.1080/14786419.2016.1169418
Abstract: Abstract Two new pimarane-type diterpenes, scopararanes H-I (1–2), along with five known ones (3–7) were isolated from the culture broth of a marine sediment-derived fungus Eutypella sp. FS46, which was obtained from the South China… read more here.
Keywords: sediment derived; derived fungus; type diterpenes; fungus eutypella ... See more keywords
SARS-CoV-2 main protease and papain-like protease inhibition by abietane-type diterpenes isolated from the branches of Glyptostrobus pensilis using molecular docking studies
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DOI: 10.1080/14786419.2022.2025801
Abstract: Abstract Using various chromatographic methods, five abietane-type diterpenes were isolated from the branches of Glyptostrobus pensilis for the first time. The chemical structures of the isolates were identified by modern spectroscopic techniques, including 1H and… read more here.
Keywords: protease; diterpenes isolated; type diterpenes; abietane type ... See more keywords
Daphnane-Type Diterpenes from Stelleropsis tianschanica and Their Antitumor Activity
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DOI: 10.3390/molecules27175701
Abstract: Four new daphnane-type diterpenes named tianchaterpenes C-F (1–4) and six known ones were isolated from Stelleropsis tianschanica. Their structures were elucidated based on chemical and spectral analyses. The comparisons of calculated and experimental electronic circular… read more here.
Keywords: daphnane type; activity; stelleropsis tianschanica; type diterpenes ... See more keywords