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   Articles with "type epithelial" as a keyword



Genotype-matched treatment for patients with advanced type I epithelial ovarian cancer (EOC).

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recommendations! Published in 2017 at "Gynecologic oncology"

DOI: 10.1016/j.ygyno.2016.12.002

Abstract: BACKGROUND Genomic alterations that activate the MAPK signaling pathway frequently occur in Type I Epithelial Ovarian Cancers (EOCs). We evaluated therapeutic response outcomes in patients with type I EOC treated with genotype-matched therapy on clinical… read more here.

Keywords: epithelial ovarian; treatment; genotype; genotype matched ... See more keywords

Dysregulated alveolar type 2 epithelial cell proteostasis promotes fibrogenic macrophage migration inhibitory factor-CD74 signaling.

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recommendations! Published in 2025 at "Science translational medicine"

DOI: 10.1126/scitranslmed.adr2277

Abstract: Aberrant proteostasis in alveolar type 2 epithelial cells (AEC2s) contributes to idiopathic pulmonary fibrosis (IPF), but the role of the ubiquitin-proteasome system (UPS) is unclear. Here, we show that UPS disruption in AEC2s amplifies profibrotic… read more here.

Keywords: mif; fibrosis; type epithelial; factor ... See more keywords

Efficacy of Alveolar Type II Epithelial Cell Transplantation for Pulmonary Fibrosis: A Meta-Analysis

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recommendations! Published in 2023 at "Iranian Journal of Public Health"

DOI: 10.18502/ijph.v52i1.11660

Abstract: Background: Cell transplantation is a promising therapeutic strategy for pulmonary fibrosis. In order to clarify the alveolar type II epithelial cell potential utility in the treatment of lung disease, we conducted a meta-analysis, to evaluate… read more here.

Keywords: cell; type epithelial; pulmonary fibrosis; alveolar type ... See more keywords

Integrative Analysis of the lncRNA-Associated ceRNA Regulatory Network Response to Hypoxia in Alveolar Type II Epithelial Cells of Tibetan Pigs

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recommendations! Published in 2022 at "Frontiers in Veterinary Science"

DOI: 10.3389/fvets.2022.834566

Abstract: The function of alveolar type II epithelial (ATII) cells is severely hampered by oxygen deficiency, and understanding the regulatory mechanisms controlling responses to hypoxia may assist in relieving injury induced by hypoxia. In this study,… read more here.

Keywords: type epithelial; cells tibetan; associated cerna; hypoxia ... See more keywords

Alternative splicing signature of alveolar type II epithelial cells of Tibetan pigs under hypoxia-induced

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recommendations! Published in 2022 at "Frontiers in Veterinary Science"

DOI: 10.3389/fvets.2022.984703

Abstract: Alternative splicing (AS) allows the generation of multiple transcript variants from a single gene and affects biological processes by generating protein diversity in organisms. In total, 41,642 AS events corresponding to 9,924 genes were identified,… read more here.

Keywords: type epithelial; alternatively spliced; alternative splicing; alveolar type ... See more keywords