Asymmetric SN2′-type C–H functionalization of arenes with propargylic alcohols
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DOI: 10.1039/c7qo00588a
Abstract: Herein we present the first example of transition metal-mediated stereodefined β-OH elimination, an atom economical [Cp*RhCl2]2-catalyzed SN2′-type coupling between easily available arenes and non-terminal tertiary 2-alkynylic alcohols at rt affording fully substituted allenes with H2O… read more here.
Keywords: asymmetric sn2; sn2 type; propargylic alcohols; type functionalization ... See more keywords