Transcriptome analysis of Panax zingiberensis identifies genes encoding oleanolic acid glucuronosyltransferase involved in the biosynthesis of oleanane-type ginsenosides
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DOI: 10.1007/s00425-018-2995-6
Abstract: Main conclusionOleanolic acid glucuronosyltransferase (OAGT) genes synthesizing the direct precursor of oleanane-type ginsenosides were discovered. The four recombinant proteins of OAGT were able to transfer glucuronic acid at C-3 of oleanolic acid that yields oleanolic… read more here.
Keywords: oleanane type; oleanolic acid; zingiberensis; type ginsenosides ... See more keywords
Highly Regioselective Biotransformation of Protopanaxadiol-type and Protopanaxatriol-type Ginsenosides in the Underground Parts of Panax notoginseng to 18 Minor Ginsenosides by Talaromyces flavus
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DOI: 10.1021/acsomega.2c00557
Abstract: The transformation of major ginsenosides to minor ginsenosides by microorganisms was considered to be an environmentally friendly method. Compared with GRAS (generally recognized as safe) strains, non-food-grade microorganisms could transform polar ginsenosides to various minor… read more here.
Keywords: type ginsenosides; minor ginsenosides; talaromyces flavus; underground parts ... See more keywords
Two new dammarane-type ginsenosides from Panax ginseng.
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DOI: 10.1080/14786419.2021.1991338
Abstract: Two new dammarane-type ginsenosides elucidated as 3-O-[β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl]-20-O-[α-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl]-20(S)-protopanaxadiol, named Ginsenoside Rb6(2); (Z)-6-O-β-D-glucopyranosyl-dammar-20(22), 24-diene-3β, 6α, 12β-triol, named (20Z)-Ginsenoside Rh4 (4); along with five known ginsenosides(1, 3, 5, 6, 7) were isolated from the radix and rhizome of… read more here.
Keywords: dammarane type; glucopyranosyl; glucopyranosyl glucopyranosyl; type ginsenosides ... See more keywords
Antineoplastic Activity, Structural Modification, Synthesis and Structure-activity Relationship of Dammarane-type Ginsenosides: An Overview
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DOI: 10.2174/1385272823666190401141138
Abstract: Dammarane-type ginsenosides are a class of tetracyclic triterpenoids with the same dammarane skeleton. These compounds have a wide range of pharmaceutical applications for neoplasms, diabetes mellitus and other metabolic syndromes, hyperlipidemia, cardiovascular and cerebrovascular diseases,… read more here.
Keywords: structural modification; dammarane type; disease; activity ... See more keywords