Production of galactosylated complex-type N-glycans in glycoengineered Saccharomyces cerevisiae
Sign Up to like & getrecommendations! Published in 2021 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-021-11727-8
Abstract: Abstract N-glycosylation is an important posttranslational modification affecting the properties and quality of therapeutic proteins. Glycoengineering in yeast aims to produce proteins carrying human-compatible glycosylation, enabling the production of therapeutic proteins in yeasts. In this… read more here.
Keywords: saccharomyces cerevisiae; complex type; production; galactosylated complex ... See more keywords
Hericium erinaceus isolectins recognize mucin-type O-glycans as tumor-associated carbohydrate antigens on the surface of K562 human leukemia cells.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.08.115
Abstract: In Hericium erinaceus mushroom fruiting body, two different lectin groups, HEL1 and HEL2, were identified by using peptide mass fingerprinting based on customized protein sequence databases derived from RNA-Seq data. The HEL2 group included four… read more here.
Keywords: associated carbohydrate; tumor associated; mucin type; type glycans ... See more keywords
Lack of complex type N-glycans lessens aberrant neuronal properties
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DOI: 10.1371/journal.pone.0199202
Abstract: Modifications in surface glycans attached to proteins via N-acetylglucosamine-β1-N-asparagine linkage have been linked to tumor development and progression. These modifications include complex N-glycans with high levels of branching, fucose and sialic acid residues. Previously, we… read more here.
Keywords: cell line; type glycans; complex type; type ... See more keywords