Methylated Bovine Serum Albumin (mBSA)-Induced Delayed-Type Hypersensitivity in Mice.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8549-4_7
Abstract: Delayed-type hypersensitivity (DTH or type IV hypersensitivity) is defined by T-cell-driven inflammation which occurs only after secondary insult with antigen. Interestingly both Th1, the classical, and Th17, the more recently discovered, proinflammatory lineages have been… read more here.
Keywords: methylated bovine; hypersensitivity; cell; type hypersensitivity ... See more keywords
Potent immunosuppressive activity of a phosphodiesterase‐4 inhibitor N‐acylhydrazone in models of lipopolysaccharide‐induced shock and delayed‐type hypersensitivity reaction
Sign Up to like & getrecommendations! Published in 2018 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2018.09.047
Abstract: &NA; Immunosuppressive drugs are widely used for the treatment of immune‐mediated diseases and inflammation, but the toxicity and side effects of the available immunosuppressors make the search of new agents of great relevance. Here, we… read more here.
Keywords: lassbio; activity; phosphodiesterase; lassbio 1386 ... See more keywords
Identification of hepatotoxic and nephrotoxic potential markers of triptolide in mice with delayed‐type hypersensitivity
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2018.08.018
Abstract: HIGHLIGHTSA strategy using HPLC‐HRMS with multivariate statistical analysis to discover toxic potential markers of triptolide was developed.Forty‐six triptolide metabolites were identified in the liver, kidney and plasma, and 27 of them might be related to… read more here.
Keywords: liver kidney; potential markers; markers triptolide; kidney plasma ... See more keywords
Combination therapy of phosphatidylserine liposome with cyclosporine A improves nephrotoxicity and attenuates delayed-type hypersensitivity response.
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DOI: 10.1016/j.lfs.2020.118780
Abstract: This study aimed to evaluate the antioxidant capacity of phosphatidylserine liposome (PS) against oxidative stress due to Cyclosporine A (CsA) and their concurrent administration on the attenuation of immune response. The effect of oral PS… read more here.
Keywords: delayed type; phosphatidylserine liposome; response; cyclosporine ... See more keywords
A randomized controlled trial with a delayed‐type hypersensitivity model using keyhole limpet haemocyanin to evaluate adaptive immune responses in man
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.14588
Abstract: Keyhole limpet haemocyanin (KLH) immunization is a clinical model for the evaluation of human antibody responses. The current study evaluated the anti‐KLH antibody response after KLH immunization and the delayed‐type hypersensitivity response following intradermal KLH… read more here.
Keywords: keyhole limpet; type hypersensitivity; limpet haemocyanin; delayed type ... See more keywords
Nadroparin carries a potentially high risk of inducing cutaneous delayed‐type hypersensitivity responses
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DOI: 10.1111/cod.12764
Abstract: Heparins are widely used for the prophylaxis/treatment of thromboembolic events. As adverse effects, heparin‐induced skin lesions occur frequently (in 7.5–39% of patients). Skin lesions may be the only clinical manifestation of life‐threatening immune‐mediated heparin‐induced thrombocytopenia,… read more here.
Keywords: heparin induced; risk; type hypersensitivity; delayed type ... See more keywords
Incidence of urticaria, angioedema, and type I hypersensitivity reactions associated with fibrinolytic agents in Thailand using the database of the health product vigilance center.
Sign Up to like & getrecommendations! Published in 2020 at "Asian Pacific journal of allergy and immunology"
DOI: 10.12932/ap-181119-0694
Abstract: BACKGROUND Besides hemorrhage, allergic reactions have also been observed in several clinical trials of fibrinolytic agents. These reactions might negatively affect patient outcomes, especially life-threatening type I hypersensitivity reactions such as anaphylaxis. However, there are… read more here.
Keywords: incidence; hypersensitivity reactions; 000 persons; type hypersensitivity ... See more keywords
Metal-induced delayed type hypersensitivity responses potentiate particle induced osteolysis in a sex and age dependent manner
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DOI: 10.1371/journal.pone.0251885
Abstract: It is widely recognized that innate macrophage immune reactions to implant debris are central to the inflammatory responses that drive biologic implant failure over the long term. Less common, adaptive lymphocyte immune reactions to implant… read more here.
Keywords: metal; particle; mice; type hypersensitivity ... See more keywords
Impact of delayed type hypersensitivity arthritis on development of heart failure by aortic constriction in mice
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DOI: 10.1371/journal.pone.0262821
Abstract: Aims Patients with rheumatoid arthritis (RA) have increased risk of heart failure (HF). The mechanisms and cardiac prerequisites explaining this association remain unresolved. In this study, we sought to determine the potential cardiac impact of… read more here.
Keywords: heart failure; hypersensitivity arthritis; type hypersensitivity; aortic constriction ... See more keywords
Methanosphaera stadtmanae induces a type IV hypersensitivity response in a mouse model of airway inflammation
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DOI: 10.14814/phy2.13163
Abstract: Despite improved awareness of work‐related diseases and preventive measures, many workers are still at high risk of developing occupational hypersensitivity airway diseases. This stems from a lack of knowledge of bioaerosol composition and their potential… read more here.
Keywords: response; airway inflammation; mss; methanosphaera stadtmanae ... See more keywords
Suckling by Schistosoma mansoni-infected mothers restored IgG2a and TGF-β production, but not IL-6 and delayed-type hypersensitivity in IL-12/IL-23-deficient mice
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DOI: 10.1590/0037-8682-0744-2020
Abstract: Abstract INTRODUCTION Suckling by schistosomotic mice improves anti-ovalbumin (OA) antibody production, while delayed-type hypersensitivity (DTH) remains unaffected. This property of milk from schistosomotic mice was investigated in IL-12/IL-23-deficient mice (IL-12p40KO). METHODS We compared anti-OA DTH,… read more here.
Keywords: production delayed; igg2a tgf; mice; deficient mice ... See more keywords