Expanding the Chemical Palette of Industrial Microbes: Metabolic Engineering for Type III PKS‐Derived Polyketides
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology Journal"
DOI: 10.1002/biot.201700463
Abstract: Polyketides are a unique class of molecules with attractive bioactive and chemical properties. As a result, biorenewable production is being explored with these molecules as potential pharmaceutical, fuel, and material precursors. In particular, type III… read more here.
Keywords: engineering; production; type iii; derived polyketides ... See more keywords
A Type III Polyketide Synthase Specific for Sporulating Negativicutes is Responsible for Alkylpyrone Biosynthesis
Sign Up to like & getrecommendations! Published in 2022 at "Chembiochem"
DOI: 10.1002/cbic.202200431
Abstract: Genomic analyses indicate that anaerobic bacteria represent a neglected source of natural products. Whereas a limited number of polyketides have been reported from anaerobes, products of type III polyketide synthases (PKSs) have remained unknown. We… read more here.
Keywords: type iii; specific sporulating; polyketide synthase; type ... See more keywords
Role of autophagy in inhibiting the proliferation of A549 cells by type III interferon
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biology International"
DOI: 10.1002/cbin.11132
Abstract: Interferons (IFNs) have anti‐viral and anti‐tumour effects. Type III interferon, as a member of the recently discovered interferon family, has been proved to inhibit tumour proliferation and promote the apoptosis of various tumour cells. However,… read more here.
Keywords: a549 cells; proliferation a549; iii interferon; proliferation ... See more keywords
Revisiting the influence of learning in predator functional response, how it can lead to shapes different from type III
Sign Up to like & getrecommendations! Published in 2022 at "Ecology and Evolution"
DOI: 10.1002/ece3.8593
Abstract: Abstract Predator/parasitoid functional response is one of the main tools used to study predation behavior, and in assessing the potential of biological control candidates. It is generally accepted that predator learning in prey searching and… read more here.
Keywords: predator; functional response; response; type iii ... See more keywords
Cardiac disease in mucopolysaccharidosis type III
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12015
Abstract: Mucopolysaccharidosis type III (MPS III; Sanfilippo disease) is primarily characterized by neurocognitive decline with limited somatic disease. Only few reports addressed cardiac disease (CD) in MPS III. We investigated the prevalence of CD in a… read more here.
Keywords: mucopolysaccharidosis type; type iii; disease; cardiac disease ... See more keywords
SARS‐CoV‐2 NSP7 inhibits type I and III IFN production by targeting the RIG‐I/MDA5, TRIF, and STING signaling pathways
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28561
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a poor inducer of innate antiviral immunity, and the underlying mechanism still needs further investigation. Here, we reported that SARS‐CoV‐2 NSP7 inhibited the production of type I… read more here.
Keywords: type iii; rig mda5; cov nsp7; sars cov ... See more keywords
SARS‐CoV‐2 NSP8 suppresses type I and III IFN responses by modulating the RIG‐I/MDA5, TRIF, and STING signaling pathways
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28680
Abstract: SARS‐CoV‐2 has developed a variety of approaches to counteract host innate antiviral immunity to facilitate its infection, replication and pathogenesis, but the molecular mechanisms that it employs are still not been fully understood. Here, we… read more here.
Keywords: type iii; rig mda5; cov nsp8; trif sting ... See more keywords
Allergy: Type I, II, III, and IV.
Sign Up to like & getrecommendations! Published in 2021 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2021_510
Abstract: Hypersensitivity reactions are overreactions of the immune system clinically seen as allergic and autoimmune diseases. Gell and Coombs originally described four different types of hypersensitivity reactions almost 60 years ago, and their description still applies in… read more here.
Keywords: hypersensitivity; pharmacology; allergy type; type iii ... See more keywords
Export Mechanisms and Energy Transduction in Type-III Secretion Machines.
Sign Up to like & getrecommendations! Published in 2019 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2019_166
Abstract: The remarkably complex architecture and organization of bacterial nanomachines originally raised the enigma to how they are assembled in a coordinated manner. Over the years, the assembly processes of the flagellum and evolutionary-related injectisome complexes… read more here.
Keywords: iii secretion; secretion; type iii; export mechanisms ... See more keywords
Transcriptional and Post-transcriptional Regulatory Mechanisms Controlling Type III Secretion.
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DOI: 10.1007/82_2019_168
Abstract: Type III secretion systems (T3SSs) are utilized by numerous Gram-negative bacteria to efficiently interact with host cells and manipulate their function. Appropriate expression of type III secretion genes is achieved through the integration of multiple… read more here.
Keywords: secretion; iii secretion; post transcriptional; transcriptional post ... See more keywords
The Structure of the Type III Secretion System Needle Complex.
Sign Up to like & getrecommendations! Published in 2019 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2019_178
Abstract: The type III secretion system (T3SS) is an essential virulence factor of many pathogenic bacterial species including Salmonella, Yersinia, Shigella and enteropathogenic Escherichia coli (EPEC). It is an intricate molecular machine that spans the bacterial… read more here.
Keywords: needle complex; secretion system; system; iii secretion ... See more keywords