Effects of Endotoxin on Type 3 Inositol 1,4,5‐Trisphosphate Receptor in Human Cholangiocytes
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DOI: 10.1002/hep.30228
Abstract: Clinical conditions that result in endotoxemia, such as sepsis and alcoholic hepatitis (AH), often are accompanied by cholestasis. Although hepatocellular changes in response to lipopolysaccharide (LPS) have been well characterized, less is known about whether… read more here.
Keywords: type inositol; effects endotoxin; human cholangiocytes; inositol trisphosphate ... See more keywords
Type 3 Inositol 1,4,5‐Trisphosphate Receptor Is Increased and Enhances Malignant Properties in Cholangiocarcinoma
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DOI: 10.1002/hep.30839
Abstract: Cholangiocarcinoma (CCA) is the second most common malignancy arising in the liver. It carries a poor prognosis, in part because its pathogenesis is not well understood. The type 3 inositol 1,4,5‐trisphosphate receptor (ITPR3) is the… read more here.
Keywords: microscopy; type inositol; cca; inositol trisphosphate ... See more keywords
Astrocytic release of ATP through type 2 inositol 1,4,5‐trisphosphate receptor calcium signaling and social dominance behavior in mice
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DOI: 10.1111/ejn.14892
Abstract: Brain mitochondrial function is critical for numerous neuronal processes. We recently identified a link between brain energy and social dominance, where higher levels of mitochondrial function resulted in increased social competitive ability. The underlying mechanism… read more here.
Keywords: atp; type inositol; mitochondrial function; social dominance ... See more keywords