Articles with "type interferonopathy" as a keyword



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Human Disease Phenotypes Associated with Loss and Gain of Function Mutations in STAT2: Viral Susceptibility and Type I Interferonopathy

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Published in 2021 at "Journal of Clinical Immunology"

DOI: 10.1007/s10875-021-01118-z

Abstract: STAT2 is distinguished from other STAT family members by its exclusive involvement in type I and III interferon (IFN-I/III) signaling pathways, and its unique behavior as both positive and negative regulator of IFN-I signaling. The… read more here.

Keywords: type interferonopathy; susceptibility; disease; stat2 ... See more keywords