Type-2-low severe asthma endotypes for new treatments: the new asthma frontier.
Sign Up to like & getrecommendations! Published in 2023 at "Current opinion in allergy and clinical immunology"
DOI: 10.1097/aci.0000000000000899
Abstract: PURPOSE OF REVIEW Type-2 (T2)-high asthma represents a well defined group of severe eosinophilic asthma for which there are now effective biologic therapies targetting the interleukins (ILs) 4, 5 and 13, and Immunoglobulin E. T2-low… read more here.
Keywords: molecular phenotypes; asthma endotypes; asthma; type low ... See more keywords
Sinonasal Biomarkers Defining Type 2-High and Type 2-Low Inflammation in Chronic Rhinosinusitis with Nasal Polyps
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12081251
Abstract: The complex pathophysiology of chronic rhinosinusitis with nasal polyps (CRSwNP) generates a spectrum of phenotypes with a wide variety of inflammatory states. We enrolled 44 very-likely-to-be type 2 CRSwNP patients in order to evaluate the… read more here.
Keywords: inflammation; chronic rhinosinusitis; type low; rhinosinusitis nasal ... See more keywords