Abstract 4605: DICER1 mutations are associated with diverse and frequently histologically mixed-type malignancies in young and adult patients
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DOI: 10.1158/1538-7445.am2018-4605
Abstract: Introduction: DICER1 is a ribonuclease III enzyme that processes pre-microRNAs into mature 20-23 nucleotide microRNAs required for their normal function. Heterozygous germline DICER1 loss-of-function mutations are associated with a cancer predisposition syndrome in which affected… read more here.
Keywords: adult; dicer1; dicer1 mutations; type malignancies ... See more keywords