Crystal structure of the CTLD7 domain of human M-type phospholipase A2 receptor.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of structural biology"
DOI: 10.1016/j.jsb.2019.06.007
Abstract: M-type phospholipase A2 receptor (PLA2R) is a member of the mannose receptor family. Recent evidence shows that PLA2R is a major autoantigen causing idiopathic membranous nephropathy (IMN), which is an autoimmune disease and one of… read more here.
Keywords: crystal structure; ctld7; structure ctld7; phospholipase receptor ... See more keywords
MiR-130a-5p prevents angiotensin II-induced podocyte apoptosis by modulating M-type phospholipase A2 receptor
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DOI: 10.1080/15384101.2018.1542901
Abstract: ABSTRACT Podocyte apoptosis is considered as the important element that promotes the development and progress of membranous nephropathy (MN). Unfortunately, the underlying mechanism of podocytes apoptosis in MN remains elusive. We compared the renal expressions… read more here.
Keywords: podocyte apoptosis; apoptosis; phospholipase receptor; type phospholipase ... See more keywords
Antibodies to M-type phospholipase A2 receptor (PLA2R) in membranous lupus nephritis
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DOI: 10.1177/0961203319828521
Abstract: Background Antibodies to M-type phospholipase A2 receptor (a-PLA2R) have been identified in most patients with idiopathic membranous nephropathy, but the prevalence in membranous lupus nephritis (MLN) is still unclear. The objective of this study was… read more here.
Keywords: antibodies type; lupus nephritis; phospholipase receptor; lupus ... See more keywords
Treatment resistant M-type phospholipase A2 receptor associated membranous nephropathy responds to obinutuzumab: a report of two cases
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DOI: 10.1186/s12882-022-02761-3
Abstract: Background Membranous Nephropathy (MN) is a common cause of nephrotic syndrome (NS) in adults. Recognition of MN as an antibody mediated autoimmune disease has enabled the introduction of anti-B-cell therapy. Rituximab, a type I anti-CD20… read more here.
Keywords: pla2r associated; phospholipase receptor; treatment; membranous nephropathy ... See more keywords
Utility of Determining Autoantibodies to M-type Phospholipase A2 Receptor in Diagnosing Primary Membranous Nephropathy: An Ideal Setting
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DOI: 10.4103/ijn.ijn_165_16
Abstract: The only study comparing PD and extended hemodialysis was carried by Ponce et al.[2] The authors randomized 143 cases of Intensive Care Unit (ICU) patients requiring dialysis to high volume peritoneal dialsysis or extended hemodialysis… read more here.
Keywords: receptor diagnosing; utility determining; determining autoantibodies; phospholipase receptor ... See more keywords