Cell Cycle Biomarkers and Soluble Urokinase-Type Plasminogen Activator Receptor for the Prediction of Sepsis-Induced Acute Kidney Injury Requiring Renal Replacement Therapy: A Prospective, Exploratory Study
Sign Up to like & getrecommendations! Published in 2019 at "Critical Care Medicine"
DOI: 10.1097/ccm.0000000000004042
Abstract: Supplemental Digital Content is available in the text. read more here.
Keywords: cycle biomarkers; urokinase type; biomarkers soluble; type plasminogen ... See more keywords
Plasma Level of Soluble Urokinase-type Plasminogen Activator Receptor Predicts the Severity of Acute Alcohol Pancreatitis
Sign Up to like & getrecommendations! Published in 2017 at "Pancreas"
DOI: 10.1097/mpa.0000000000000730
Abstract: Objectives Systemic levels of soluble urokinase-type plasminogen activator receptor (suPAR) are increased in various inflammatory and infectious diseases. We investigated the activation and prognostic value of plasma suPAR (P-suPAR) in patients experiencing their first acute… read more here.
Keywords: pancreatitis; type plasminogen; urokinase type; supar ... See more keywords
Prognostic value of soluble urokinase‐type plasminogen activator receptor in coronary artery disease: A meta‐analysis
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Clinical Investigation"
DOI: 10.1111/eci.13867
Abstract: A potential inflammatory biomarker, soluble urokinase‐type plasminogen activator receptor (suPAR) has been utilized to assist the prognostic assessment of coronary artery disease (CAD) patients; however, outcomes have been inconsistent. The prognostic relevance of suPAR as… read more here.
Keywords: soluble urokinase; activator receptor; plasminogen activator; type plasminogen ... See more keywords
Compaction of fibrin clots reveals the antifibrinolytic effect of factor XIII: reply
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.13544
Abstract: Danø K, Carmeliet P, Collen D, Degen JL. Urokinase-type plasminogen activator is effective in fibrin clearance in the absence of its receptor or tissue-type plasminogen activator. Proc Natl Acad Sci USA 1996; 93: 5899–904. 7… read more here.
Keywords: type plasminogen; compaction fibrin; reveals antifibrinolytic; fibrin clots ... See more keywords
What is the Role of Soluble Urokinase-Type Plasminogen Activator in Renal Disease?
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DOI: 10.1159/000490118
Abstract: Context: Soluble urokinase-type plasminogen activator (suPAR) is an inflammatory signal with pleiotropic biological effects depending on context and post-translational modifications. Recently, [Hayek, et al: Nat Med 2017; 23: 945–953] it has been found that there… read more here.
Keywords: type plasminogen; renal disease; urokinase type; disease ... See more keywords
Microfluidic Modeling of Thrombolysis: Effect of Antiplatelet and Anticoagulant Agents on tPA (Tissue-Type Plasminogen Activator)-Induced Fibrinolysis
Sign Up to like & getrecommendations! Published in 2018 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atvbaha.118.311178
Abstract: Objective— Despite the high clinical relevance of thrombolysis, models for its study in human flowing blood are lacking. Our objective was to develop a microfluidic model for comparative evaluation of thrombolytic therapeutic strategies. Approach and… read more here.
Keywords: type plasminogen; thrombolysis; fibrinolysis; tissue type ... See more keywords
Agreement Among Stroke Faculty and Fellows in Treating Ischemic Stroke Patients With Tissue-Type Plasminogen Activator and Thrombectomy
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DOI: 10.1161/strokeaha.116.015214
Abstract: Background and Purpose— The aim of this study is to determine agreement among vascular neurology fellows and faculty in treating patients with acute ischemic stroke with intravenous tissue-type plasminogen activator and intra-arterial thrombectomy (IAT). Methods—… read more here.
Keywords: neurology; type plasminogen; agreement; tissue type ... See more keywords
Tissue-type plasminogen activator regulates macrophage activation and innate immunity.
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DOI: 10.1182/blood-2017-04-780205
Abstract: Tissue-type plasminogen activator (tPA) is the major intravascular activator of fibrinolysis and a ligand for receptors involved in cell signaling. In cultured macrophages, tPA inhibits the response to lipopolysaccharide (LPS) by a pathway that apparently… read more here.
Keywords: type plasminogen; tissue type; tpa; activator ... See more keywords
The cAMP-ERK1/2 signaling pathway regulates urokinase-type plasminogen activator-induced bovine granulosa cell proliferation.
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DOI: 10.1530/rep-20-0165
Abstract: Although urokinase-type plasminogen activator (PLAU) and urokinase-type plasminogen activator receptor (PLAUR) have been reported to play key roles in ovarian function, their precise contribution to mammalian follicular development remains unclear. In this study, we firstly… read more here.
Keywords: type plasminogen; urokinase type; plau plaur; proliferation ... See more keywords
Soluble Urokinase-type Plasminogen Activator Receptor Predicts All-cause 5-Year Mortality in Ischemic Stroke and TIA.
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DOI: 10.21873/invivo.11070
Abstract: AIM We evaluated soluble urokinase-type plasminogen activator receptor (suPAR) levels in different stroke subtypes and assessed their prognostic value regarding 5-year outcomes. MATERIALS AND METHODS The study included 117 stroke patients (81 males; mean=age 61±11… read more here.
Keywords: type plasminogen; urokinase type; year; mortality ... See more keywords
Plasma Levels of Tissue-Type Plasminogen Activator (tPA) in Normal Aging and Alzheimer's Disease: Links With Cognition, Brain Structure, Brain Function and Amyloid Burden
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DOI: 10.3389/fnagi.2022.871214
Abstract: Tissue-type plasminogen activator (tPA) is a protease known for its fibrinolytic action but is also involved in physiological and pathophysiological aging processes; including amyloid elimination and synaptic plasticity. The aim of the study was to… read more here.
Keywords: tissue type; plasminogen activator; brain; tpa ... See more keywords