Global characterization of macrophage polarization mechanisms and identification of M2-type polarization inhibitors.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109955
Abstract: Macrophages undergoing M1- versus M2-type polarization differ significantly in their cell metabolism and cellular functions. Here, global quantitative time-course proteomics and phosphoproteomics paired with transcriptomics provide a comprehensive characterization of temporal changes in cell metabolism,… read more here.
Keywords: metabolism; macrophage polarization; polarization; type polarization ... See more keywords
MicroRNA-223 modulates the IL-4-medicated macrophage M2-type polarization to control the progress of sepsis.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.107783
Abstract: MicroRNAs play a variety of roles in the progress of inflammation. Herein, we investigated the roles of miR-223 in governing macrophage polarization balance in the progress of sepsis. We firstly observed that miR-223 was down-regulated… read more here.
Keywords: progress sepsis; mir 223; type polarization; polarization ... See more keywords