Articles with "type ubiquitin" as a keyword



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Promising new therapeutic targets for regulation of inflammation and immunity: RING-type E3 ubiquitin ligases.

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Published in 2018 at "Immunology letters"

DOI: 10.1016/j.imlet.2018.08.001

Abstract: Ubiquitin-proteasome system (UPS) is a primary signaling pathway for regulation of protein turnover and removal of misfolded proteins in eukaryotic cells. Enzymes of the UPS pathway - E1 activating, E2 conjugating, E3 ligating - act… read more here.

Keywords: ring type; type ubiquitin; inflammation immunity; ubiquitin ligases ... See more keywords
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HECT-Type E3 Ubiquitin Ligases in Cancer.

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Published in 2019 at "Trends in biochemical sciences"

DOI: 10.1016/j.tibs.2019.08.004

Abstract: Ubiquitination, a post-translational modification that involves a covalent attachment of ubiquitin to a protein substrate, is essential for cellular homeostatic maintenance. At the end of a three-enzyme cascade, E3 ubiquitin ligases (E3s) recruit substrates and… read more here.

Keywords: ligases cancer; type ubiquitin; hect type; ubiquitin ligases ... See more keywords
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Involvement of HECT-type E3 ubiquitin ligase genes in salt chemotaxis learning in C. elegans.

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Published in 2022 at "Genetics"

DOI: 10.1093/genetics/iyac025

Abstract: The ubiquitin-proteasome system is associated with various phenomena including learning and memory. In this paper, we report that E3 ubiquitin ligase homologs and the proteasome function are involved in taste avoidance learning, a type of… read more here.

Keywords: ligase genes; ubiquitin ligase; avoidance learning; hect type ... See more keywords
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RING-Type E3 Ubiquitin Ligases AtRDUF1 and AtRDUF2 Positively Regulate the Expression of PR1 Gene and Pattern-Triggered Immunity

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms232314525

Abstract: The importance of E3 ubiquitin ligases from different families for plant immune signaling has been confirmed. Plant RING-type E3 ubiquitin ligases are members of the E3 ligase superfamily and have been shown to play positive… read more here.

Keywords: expression; ligases atrduf1; ubiquitin ligases; ring type ... See more keywords