Dental phenotype in an adolescent with osteogenesis imperfecta type XII
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2021-246554
Abstract: Mutation in SP7, encoding the osteoblast-specific transcription factor SP7 (also known as osterix), has been described to cause osteogenesis imperfecta (OI) type XII. However, the exact dental phenotype has not been well described. We report… read more here.
Keywords: type xii; xii; imperfecta type; dental phenotype ... See more keywords
Collagen type XII is undetectable in keratoconus Bowman’s layer
Sign Up to like & getrecommendations! Published in 2023 at "British Journal of Ophthalmology"
DOI: 10.1136/bjo-2022-322180
Abstract: Purpose Corneal biomechanical failure is the hallmark of keratoconus (KC); however, the cause of this failure remains elusive. Collagen type XII (COL12A1), which localises to Bowman’s layer (BL), is thought to function in stress-bearing areas,… read more here.
Keywords: type xii; collagen type; col12a1; keratoconus ... See more keywords
Abstract 137: Type XII collagen is elevated in serum from patients with solid tumors: A non-invasive biomarker of activated fibroblasts
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-137
Abstract: The tumor microenvironment (TME) and extracellular matrix (ECM) are critical to tumor progression and treatment outcomes. Collagens, the main ECM components, influence cell signaling, migration, and tumor invasion. Type XII collagen is essential for type… read more here.
Keywords: collagen; type xii; cancer; xii collagen ... See more keywords