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   Articles with "typhi" as a keyword



Characteristics of regulatory T-cell populations before and after Ty21a typhoid vaccination in children and adults.

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recommendations! Published in 2019 at "Clinical immunology"

DOI: 10.1016/j.clim.2019.04.002

Abstract: Typhoid fever, caused by the pathogen Salmonella enterica serovar Typhi (S. Typhi), is a serious global health concern. Challenge studies with wild type S. Typhi identified associations between gut-homing regulatory T cells (Treg) and development… read more here.

Keywords: typhi; regulatory cell; characteristics regulatory; ty21a vaccination ... See more keywords

Extensively Drug-Resistant Salmonella enterica serovar Typhi in Pediatric population during CoVID-19 Pandemic

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recommendations! Published in 2022 at "International Journal of Infectious Diseases"

DOI: 10.1016/j.ijid.2021.12.010

Abstract: Purpose The Extensively Drug-resistant (XDR) Salmonella isolates exhibiting resistance to the first line and the second-line antibiotic options are presently a grave public health concern in Pakistan. Here, we report the first large-scale emergence and… read more here.

Keywords: resistance; drug resistant; extensively drug; salmonella ... See more keywords

A 3' UTR-derived non-coding RNA RibS increases expression of cfa and promotes biofilm formation of Salmonella enterica serovar Typhi.

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recommendations! Published in 2018 at "Research in microbiology"

DOI: 10.1016/j.resmic.2018.04.007

Abstract: Bacterial non-coding RNAs (ncRNAs) are widely studied and found to play important roles in regulating various cellular processes. Recently, many ncRNAs have been discovered to be transcribed or processed from 3' untranslated regions (3' UTRs).… read more here.

Keywords: typhi; biofilm formation; ribs; non coding ... See more keywords
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Identification of novel vaccine candidate against Salmonella enterica serovar Typhi by reverse vaccinology method and evaluation of its immunization.

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recommendations! Published in 2020 at "Genomics"

DOI: 10.1016/j.ygeno.2020.06.022

Abstract: Salmonella enterica serovar Typhi (S. Typhi) is an essential enteric fever causing bacterium worldwide. Due to the emergence of multidrug-resistant strains, urgently attention is needed to prevent the global spread of them. Vaccination is an… read more here.

Keywords: typhi; enterica serovar; salmonella enterica; serovar typhi ... See more keywords

Salmonella Typhi gut invasion drives hypoxic immune subsets associated with disease outcomes

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recommendations! Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-62136-8

Abstract: Salmonella Typhi (S. Typhi), the causative agent of typhoid disease, remains a major public health concern. Owing to the human-restricted nature of S. Typhi, studies of typhoid pathogenesis in animal models are limited to a… read more here.

Keywords: disease; gut invasion; signature; model ... See more keywords

Augmented antibiotic resistance associated with cadmium induced alterations in Salmonella enterica serovar Typhi

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recommendations! Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-31143-9

Abstract: In view of the reports on co-selection of metal and antibiotic resistance, recently we have reported that increased cadmium accumulation in Salmonella Typhi Ty2 leads to increased antibiotic resistance. In continuation, the present study was… read more here.

Keywords: typhi; salmonella; cadmium accumulation; resistance ... See more keywords

Transcriptional profiling links unique human macrophage phenotypes to the growth of intracellular Salmonella enterica serovar Typhi

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recommendations! Published in 2024 at "Scientific Reports"

DOI: 10.1038/s41598-024-63588-6

Abstract: Macrophages provide a crucial environment for Salmonella enterica serovar Typhi (S. Typhi) to multiply during typhoid fever, yet our understanding of how human macrophages and S. Typhi interact remains limited. In this study, we delve… read more here.

Keywords: enterica serovar; serovar typhi; salmonella enterica; typhi ... See more keywords

Rational design of a multi epitope vaccine against Salmonella typhi via subtractive proteomics, reverse vaccinology and molecular modeling

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recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-15254-8

Abstract: Salmonella enterica subsp. enterica serotype Typhi (Salmonella typhi) is the cause of typhoid fever, a severe public health issue in impoverished countries with inadequate sanitation. Despite the availability of therapies, infection rates remain high, underscoring… read more here.

Keywords: salmonella; multi epitope; typhi; vaccine ... See more keywords
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[Typhoid and paratyphoid fever].

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recommendations! Published in 2020 at "Zeitschrift fur Gastroenterologie"

DOI: 10.1055/a-1063-1945

Abstract: Typhoid fever and paratyphoid fever are systemic infectious diseases of global significance caused by Salmonella enterica subspecies enterica Serovar Typhi (short name: Salmonella Typhi) or Serovar Paratyphi (short name: Salmonella Paratyphi). The course of these… read more here.

Keywords: typhi; salmonella; fever; paratyphoid fever ... See more keywords

Propionylation of Fis K32 in Salmonella enterica serovar Typhi: a key modification affecting pathogenicity.

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recommendations! Published in 2025 at "Future microbiology"

DOI: 10.1080/17460913.2025.2460338

Abstract: AIM This study aims to explore the role of propionylation at the K32 residue of the global regulator Fis in Salmonella enterica serovar Typhi (S. Typhi) and its influence on the pathogenicity of the bacteria.… read more here.

Keywords: pathogenicity; propionylation; fis; salmonella enterica ... See more keywords

Diversity of Salmonella Typhi-responsive CD4 and CD8 T cells before and after Ty21a typhoid vaccination in children and adults.

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recommendations! Published in 2019 at "International immunology"

DOI: 10.1093/intimm/dxz011

Abstract: Typhoid fever is a life-threatening disease caused by the human-restricted pathogen Salmonella enterica serovar Typhi (S. Typhi). The oral live attenuated Ty21a typhoid vaccine protects against this severe disease by eliciting robust, multifunctional cell-mediated immunity… read more here.

Keywords: typhi; cd8; typhi responsive; ty21a typhoid ... See more keywords