Detection of typhoid fever by diatom-based optical biosensor
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-017-9362-1
Abstract: Surface-modified diatom substrates are employed for the development of immunocomplex-based optical biosensor for diagnosis of typhoid. Biosensor has been prepared by covalent immobilization of Salmonella typhi antibody onto the crosslinked diatom substrates via glutaraldehyde. Photoluminescent… read more here.
Keywords: diatom substrates; biosensor; diatom; typhoid ... See more keywords
The phylogeography and incidence of multi-drug resistant typhoid fever in sub-Saharan Africa
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-07370-z
Abstract: There is paucity of data regarding the geographical distribution, incidence, and phylogenetics of multi-drug resistant (MDR) Salmonella Typhi in sub-Saharan Africa. Here we present a phylogenetic reconstruction of whole genome sequenced 249 contemporaneous S. Typhi… read more here.
Keywords: typhoid; sub saharan; saharan africa; multi drug ... See more keywords
[Typhoid and paratyphoid fever].
Sign Up to like & getrecommendations! Published in 2020 at "Zeitschrift fur Gastroenterologie"
DOI: 10.1055/a-1063-1945
Abstract: Typhoid fever and paratyphoid fever are systemic infectious diseases of global significance caused by Salmonella enterica subspecies enterica Serovar Typhi (short name: Salmonella Typhi) or Serovar Paratyphi (short name: Salmonella Paratyphi). The course of these… read more here.
Keywords: typhi; salmonella; fever; paratyphoid fever ... See more keywords
Progress in the overall understanding of typhoid fever: implications for vaccine development
Sign Up to like & getrecommendations! Published in 2020 at "Expert Review of Vaccines"
DOI: 10.1080/14760584.2020.1750375
Abstract: ABSTRACT Introduction Typhoid fever continues to have a substantial impact on human health, especially in Asia and sub-Saharan Africa. Access to safe water, and adequate sanitation and hygiene remain the cornerstone of prevention, but these… read more here.
Keywords: progress overall; typhoid fever; understanding typhoid; control ... See more keywords
Typhoid conjugate vaccines: is a single dose enough for durable protection?
Sign Up to like & getrecommendations! Published in 2025 at "Expert review of vaccines"
DOI: 10.1080/14760584.2025.2476525
Abstract: ABSTRACT Introduction Typhoid fever is widespread in developing countries. Most typhoid vaccines have gone into some disrepute for their substantial side effects and low efficacy. The latest typhoid vaccines use Salmonella‘s Vi-capsular polysaccharide (Vi-CPS) conjugated… read more here.
Keywords: typhoid; single dose; typhoid conjugate; efficacy ... See more keywords
Using Typhoid Conjugate Vaccines to Prevent Disease, Promote Health Equity, and Counter Drug-Resistant Typhoid Fever
Sign Up to like & getrecommendations! Published in 2023 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofad022
Abstract: Abstract Typhoid fever is a serious disease that disproportionately impacts children in low-resource settings in sub-Saharan Africa, South and Southeast Asia, and the Western Pacific. The prevalence of antimicrobial-resistant strains of S. Typhi continue to… read more here.
Keywords: typhoid conjugate; typhoid; typhoid fever; conjugate vaccines ... See more keywords
What Should We Be Recommending for the Treatment of Enteric Fever?
Sign Up to like & getrecommendations! Published in 2023 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofad179
Abstract: Abstract Patients with suspected enteric (typhoid and paratyphoid) fever are predominantly managed as outpatients in endemic regions. Nonspecific clinical presentation, lack of accurate diagnostic tools, and widespread antimicrobial resistance makes management challenging. Resistance has been… read more here.
Keywords: typhoid; recommending treatment; fever; treatment enteric ... See more keywords
Generation and Characterization of Typhoid Toxin-Neutralizing Human Monoclonal Antibodies
Sign Up to like & getrecommendations! Published in 2020 at "Infection and Immunity"
DOI: 10.1128/iai.00292-20
Abstract: Typhoid toxin is a virulence factor of Salmonella enterica serovar Typhi, the causative agent of typhoid fever, and is thought to be responsible for the symptoms of severe disease. This toxin has a unique A2B5… read more here.
Keywords: monoclonal antibodies; toxin neutralizing; toxin; generation characterization ... See more keywords
Evaluation of a point-of-care multiplex immunochromatographic assay for the diagnosis of typhoid: results from a retrospective diagnostic accuracy study
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.00428-24
Abstract: ABSTRACT There is a clear medical need for an accurate diagnostic test for typhoid that can be performed at point of care. Two antigens (lipopolysaccharide [LPS] and hemolysin E [HlyE]) have recently been identified that… read more here.
Keywords: typhoid; specificity; test; accuracy ... See more keywords
Molecular Insights into the Assembly and Functional Diversification of Typhoid Toxin
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.01916-21
Abstract: Typhoid fever is a devastating disease that kills more than 115,000 people every year and is caused by Salmonella Typhi. Typhoid toxin, exclusively produced by S. ABSTRACT Typhoid toxin is an A2B5 protein toxin and… read more here.
Keywords: typhoid toxin; typhoid; pltc; typhoid fever ... See more keywords
Quantifying antibiotic use in typhoid fever in India: a cross-sectional analysis of private sector medical audit data, 2013–2015
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Open"
DOI: 10.1136/bmjopen-2022-062401
Abstract: Objectives To estimate the antibiotic prescription rates for typhoid in India. Design Cross-sectional study. Setting Private sector primary care clinicians in India. Participants The data came from prescriptions of a panel of 4600 private sector… read more here.
Keywords: prescription; typhoid; sector; cross sectional ... See more keywords