Safety and immunogenicity of a Vi-DT typhoid conjugate vaccine: Phase I trial in Healthy Filipino adults and children
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2018.05.038
Abstract: Highlights • Vi-DT is safe and well tolerated in participants aged 2–45 years.• Significantly higher immune responses post Vi-DT compared to Vi polysaccharide vaccine.• No further increase in GMT post second dose as compared to post… read more here.
Keywords: typhoid conjugate; conjugate vaccine; safety immunogenicity; immunogenicity typhoid ... See more keywords
Typhoid conjugate vaccines: is a single dose enough for durable protection?
Sign Up to like & getrecommendations! Published in 2025 at "Expert review of vaccines"
DOI: 10.1080/14760584.2025.2476525
Abstract: ABSTRACT Introduction Typhoid fever is widespread in developing countries. Most typhoid vaccines have gone into some disrepute for their substantial side effects and low efficacy. The latest typhoid vaccines use Salmonella‘s Vi-capsular polysaccharide (Vi-CPS) conjugated… read more here.
Keywords: typhoid; single dose; typhoid conjugate; efficacy ... See more keywords
Prevention of enteric fever in travellers with typhoid conjugate vaccines.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of travel medicine"
DOI: 10.1093/jtm/tay120
Abstract: The 2018 WHO position paper on typhoid vaccines indicates preference for the use of new generation typhoid conjugate vaccines over existing parenteral Vi-polysaccharide (Vi-PS) and oral attenuated Ty21a vaccines read more here.
Keywords: prevention enteric; enteric fever; typhoid conjugate; fever travellers ... See more keywords
Using Typhoid Conjugate Vaccines to Prevent Disease, Promote Health Equity, and Counter Drug-Resistant Typhoid Fever
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DOI: 10.1093/ofid/ofad022
Abstract: Abstract Typhoid fever is a serious disease that disproportionately impacts children in low-resource settings in sub-Saharan Africa, South and Southeast Asia, and the Western Pacific. The prevalence of antimicrobial-resistant strains of S. Typhi continue to… read more here.
Keywords: typhoid conjugate; typhoid; typhoid fever; conjugate vaccines ... See more keywords
Comparison of anti-Vi IgG responses between two clinical studies of typhoid Vi conjugate vaccines (Vi-DT vs Vi-TT)
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DOI: 10.1371/journal.pntd.0008171
Abstract: Salmonella enterica serovar Typhi (S. Typhi) is a causative agent for typhoid fever and especially critical in developing countries. Although clinical studies for various typhoid conjugate vaccines (TCVs) have been performed, there are no comparative… read more here.
Keywords: clinical studies; vacczyme elisa; typhoid conjugate; comparison anti ... See more keywords
Immunogenicity and Safety Profile of Typhoid Conjugate Vaccine (Vi-DT) Among Nepali Children.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Nepal Health Research Council"
DOI: 10.33314/jnhrc.v23i01.5251
Abstract: BACKGROUND Typhoid fever remains a major concern in tropical countries. The availability of an effective vaccine could be an important inclusion to currently available interventions. We reported on our evaluation of the immunogenicity and safety… read more here.
Keywords: typhoid conjugate; vaccine among; immunogenicity safety; conjugate vaccine ... See more keywords