Comparison of the inducibility of CYP mRNA exposed to typical inducers in fresh and cryopreserved cynomolgus monkey hepatocytes.
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DOI: 10.1016/j.dmpk.2020.03.001
Abstract: Herein, we evaluated CYPs and their nuclear receptor mRNA induction by exposure to typical inducers, omeprazole, rifampicin, and phenobarbital in cynomolgus monkey hepatocytes. Six freshly-isolated hepatocytes and 6 cryopreserved hepatocytes from cynomolgus monkey liver were… read more here.
Keywords: cyp mrna; cynomolgus monkey; culture; typical inducers ... See more keywords