Null alleles and sequence variations at primer binding sites of STR loci within multiplex typing systems.
Sign Up to like & getrecommendations! Published in 2018 at "Legal medicine"
DOI: 10.1016/j.legalmed.2017.10.007
Abstract: Rare variants are widely observed in human genome and sequence variations at primer binding sites might impair the process of PCR amplification resulting in dropouts of alleles, named as null alleles. In this study, 5… read more here.
Keywords: typing systems; null alleles; primer binding; sequence variations ... See more keywords
P750 A comparison of treponema pallidum molecular typing systems: mlst vs. ecdct
Sign Up to like & getrecommendations! Published in 2019 at "Sexually Transmitted Infections"
DOI: 10.1136/sextrans-2019-sti.808
Abstract: Background Several syphilis typing systems have been proposed. Recent work suggests that multilocus sequence typing (MLST) may be superior to enhanced CDC typing (ECDCT), particularly because ECDCT type may differ among organisms amplified from different… read more here.
Keywords: treponema pallidum; typing systems; ecdct; blood ... See more keywords