Tyrosinase-activated Nanocomposites for Double-modals Imaging Guided Photodynamic and Photothermal Synergistic Therapy.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300327
Abstract: Tyrosinase (TYR) is an important biomarker of melanoma. The exploration of fluorescent pr-obes-based composites is beneficial to build an integrative platform for the diagnosis and trea-tment of melanoma. Herein, we developed a multifunctional nanocomposite IOBOH@BSA… read more here.
Keywords: tyr; ioboh bsa; melanoma; photodynamic photothermal ... See more keywords
Novel potential type electrochemical chiral recognition biosensor for amino acid
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Solid State Electrochemistry"
DOI: 10.1007/s10008-017-3719-8
Abstract: AbstractNovel potential type electrochemical chiral biosensing system with unique capability of distinguishing and quantitating of tyrosine (Tyr) enantiomers by L-cysteic acid and left-handed chiral carbonaceous nanotubes (L-CCNT) modified glassy carbon electrode (L-Cys/L-CCNT/GCE) was first developed.… read more here.
Keywords: potential type; chiral recognition; tyr; electrochemical chiral ... See more keywords
Effect of GO nanosheets on spectrophotometric determination of tyrosine in urine and serum using nitrosonaphthol.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2018.07.024
Abstract: Here, we aimed to use graphene oxide to improve the selectivity and sensitivity of Tyr determination via the reaction with 1-nitroso-2-naphthol as a selective reagent of Tyr. The reaction between Tyr and 1-nitroso-2-naphthol in absence… read more here.
Keywords: presence; urine serum; determination; nitroso naphthol ... See more keywords
Tyrosinase immobilization on aminated magnetic nanoparticles by physical adsorption combined with covalent crosslinking with improved catalytic activity, reusability and storage stability.
Sign Up to like & getrecommendations! Published in 2018 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2017.12.022
Abstract: In the present study, the immobilization method of physical adsorption combined with covalent crosslinking was developed to avoid the shortcomings of both the noncovalent and covalent coupling methods. For the first time, tyrosinase (TYR) was… read more here.
Keywords: storage; immobilization; tyr; covalent crosslinking ... See more keywords
Fast-response fluorescent probe with favorable water solubility for highly sensitive imaging of endogenous tyrosinase in living cells and zebrafish model
Sign Up to like & getrecommendations! Published in 2021 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2020.12.053
Abstract: Abstract Tyrosinase (TYR) is an important polyphenolic oxidase enzyme and usually regards as a biomarker of melanoma cancer. Highly effective tracking TYR activity in vivo will help to study the mechanism of TYR in living… read more here.
Keywords: dopa; tyr activity; chmc dopa; tyr ... See more keywords
The combined toxicity of UV/chlorinated products from binary ibuprofen (IBP) and tyrosine (Tyr) on Escherichia coli: Emphasis on their occurrence and underlying mechanism.
Sign Up to like & getrecommendations! Published in 2018 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2018.07.034
Abstract: In this study, the combined toxicity of UV/chlorinated products on Escherichia coli (E. coli) was investigated when ibuprofen (IBP) and tyrosine (Tyr) were used as two precursors. The median-effect equation and combined index (CI)-isobologram equation were… read more here.
Keywords: escherichia coli; tyr; toxicity; chlorinated products ... See more keywords
Synthesis and biological evaluation of phthalocyanine-peptide conjugate for EGFR-targeted photodynamic therapy and bioimaging
Sign Up to like & getrecommendations! Published in 2019 at "Dyes and Pigments"
DOI: 10.1016/j.dyepig.2018.11.055
Abstract: Abstract To improve the biocompatibility and tumor selectivity, we employed an epidermal growth factor receptor (EGFR) binding peptide (namely GE11, with a sequence of Tyr-His-Trp-Tyr-Gly-Tyr-Thr-Pro-Gln-Asn-Val-Ile) as a tumor directing vector for the delivery of zinc(II)… read more here.
Keywords: targeted photodynamic; tyr; therapy bioimaging; peptide ... See more keywords
Identification and characterization of the tyrosinase gene (TYR) and its transcript variants (TYR_1 and TYR_2) in the crab-eating macaque (Macaca fascicularis).
Sign Up to like & getrecommendations! Published in 2017 at "Gene"
DOI: 10.1016/j.gene.2017.07.047
Abstract: Tyrosinase is a copper-containing enzyme that regulates melanin biosynthesis and is encoded by the tyrosinase (TYR) gene. Previous studies demonstrated that mutations in TYR could lead to oculocutaneous albinism type 1 (OCA1) owing to the… read more here.
Keywords: tyr crab; tyr tyr; tyrosinase; gene ... See more keywords
An electrochemical sensor for enantiorecognition of tyrosine based on a chiral macrocycle functionalized rGO
Sign Up to like & getrecommendations! Published in 2021 at "Microchemical Journal"
DOI: 10.1016/j.microc.2021.105949
Abstract: Abstract A novel chiral sensor was developed to produce the distinguishing response to the enantiomers of tyrosine (Tyr), with high sensitivity and selectivity. The electrochemical sensor was modified by the inorganic-organic nanohybrid material with the… read more here.
Keywords: tyr; tyr tyr; spectroscopy; tyr enantiomers ... See more keywords
Peroxynitrite nitration of Tyr 56 in Hsp90 induces PC12 cell death through P2X7R-dependent PTEN activation
Sign Up to like & getrecommendations! Published in 2022 at "Redox Biology"
DOI: 10.1016/j.redox.2022.102247
Abstract: The diffusion-limited reaction of nitric oxide (NO) and superoxide (O2−) produces peroxynitrite (ONOO−), a biological oxidant that has been implicated in a number of pathological conditions, including neurodegenerative disorders. We previously reported that incubation of… read more here.
Keywords: tyr; cell death; nitration; cell ... See more keywords
Sensing tyrosine enantiomers by using chiral CdSe/CdS quantum dots capped with N-acetyl-l-cysteine.
Sign Up to like & getrecommendations! Published in 2017 at "Talanta"
DOI: 10.1016/j.talanta.2016.10.091
Abstract: Despite of the importance of enantiomers, the fluorescence sensing of enantiomers and the interpretation of the "preferential interaction" still remain insufficiently explored. In this study, we report the recognition of tyrosine (Tyr) enantiomers by chiral… read more here.
Keywords: tyrosine; acetyl cysteine; cds quantum; cdse cds ... See more keywords