Biological and In silico Studies on Synthetic Analogues of Tyrosine Betaine as Inhibitors of Neprilysin - A Drug Target for the Treatment of Heart Failure.
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DOI: 10.2174/1381612824666180515114236
Abstract: BACKGROUND Fungal secondary metabolites are important sources for the discovery of new pharmaceuticals, as exemplified by penicillin, lovastatin and cyclosporine. Searching for secondary metabolites of the fungi Metarhizium spp., we previously identified tyrosine betaine as… read more here.
Keywords: heart failure; treatment heart; tyrosine betaine; inhibitors neprilysin ... See more keywords