Targeting glioma-initiating cells via the tyrosine metabolic pathway.
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DOI: 10.3171/2019.11.jns192028
Abstract: OBJECTIVE Despite an aggressive multimodal therapeutic regimen, glioblastoma (GBM) continues to portend a grave prognosis, which is driven in part by tumor heterogeneity at both the molecular and cellular levels. Accordingly, herein the authors sought… read more here.
Keywords: tyrosine metabolic; metabolic pathway; core; glioma initiating ... See more keywords