Articles with "tyrosine receptor" as a keyword



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In vitro and clinical investigations to determine the drug-drug interaction potential of entrectinib, a small molecule inhibitor of neurotrophic tyrosine receptor kinase (NTRK)

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Published in 2021 at "Investigational New Drugs"

DOI: 10.1007/s10637-021-01156-9

Abstract: Background Entrectinib is a CNS-active, potent inhibitor of tyrosine receptor kinases A/B/C, ROS1 and anaplastic lymphoma kinase approved for use in patients with solid tumors. We describe the in vitro and clinical studies investigating potential… read more here.

Keywords: inhibitor; entrectinib; vitro clinical; drug ... See more keywords
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Targeting tyrosine receptor kinase B in gliomas.

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Published in 2017 at "Neuro-oncology"

DOI: 10.1093/neuonc/now199

Abstract: We read with great interest the recent article by Ni et al.1 on the role of the tyrosine receptor kinase B (TrkB) as a drug target for the treatment of astrocytomas. Among central nervous system… read more here.

Keywords: receptor kinase; kinase; tyrosine receptor; role ... See more keywords