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Published in 2021 at "Investigational New Drugs"
DOI: 10.1007/s10637-021-01156-9
Abstract: Background Entrectinib is a CNS-active, potent inhibitor of tyrosine receptor kinases A/B/C, ROS1 and anaplastic lymphoma kinase approved for use in patients with solid tumors. We describe the in vitro and clinical studies investigating potential…
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Keywords:
inhibitor;
entrectinib;
vitro clinical;
drug ... See more keywords
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Published in 2017 at "Neuro-oncology"
DOI: 10.1093/neuonc/now199
Abstract: We read with great interest the recent article by Ni et al.1 on the role of the tyrosine receptor kinase B (TrkB) as a drug target for the treatment of astrocytomas. Among central nervous system…
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Keywords:
receptor kinase;
kinase;
tyrosine receptor;
role ... See more keywords