Design, synthesis, DNA binding studies and evaluation of anticancer potential of novel substituted biscarbazole derivatives against human glioma U87 MG cell line.
Sign Up to like & getrecommendations! Published in 2020 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2020.103911
Abstract: In this research paper, we report the design and synthesis of novel substituted biscarbazole derivatives which were characterized by 1H and 13C NMR, high resolution mass spectroscopy (HRMS). The SAR study of the compounds is… read more here.
Keywords: novel; cell line; human glioma; biscarbazole derivatives ... See more keywords
Neurotoxicity and Structure-Activity Relationships of Resveratrol and its two Natural Analogs, 4,4′-Dihydroxystilbene and Pinosylvin
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DOI: 10.1177/1934578x221113707
Abstract: Resveratrol (RES) and its two natural analogues, 4,4′-dihydroxystilbene (DHS) and pinosylvin (PIN), are very important polyphenols and have attracted considerable pharmaceutical interest because of their diverse biological activities. However, their adverse effects on motor nerves… read more here.
Keywords: structure activity; u87 cell; groups positions; hydroxyl groups ... See more keywords
Differences in Protein Expression between the U251 and U87 Cell Lines.
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DOI: 10.5137/1019-5149.jtn.17746-16.1
Abstract: AIM The U251 and U87 cell lines are commonly used as experimental models of glioblastoma. However, these cells exhibit significant differences in their proliferation, invasion, and migration. The aim of the present study was to… read more here.
Keywords: protein expression; u251 u87; cell lines; u87 cell ... See more keywords