Silencing UBE2K inhibits the growth of glioma cells by inducing the autophagy‐related apoptosis
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23758
Abstract: Glioma is a central nervous system (CNS) malignant tumor with high heterogeneity and mortality, which severely threatens the health of patients. The overall survival of glioma patients is relatively short and it is critical to… read more here.
Keywords: autophagy related; growth glioma; u87 u251; u251 cells ... See more keywords
Sevoflurane Induces Ferroptosis of Glioma Cells Through Activating the ATF4-CHAC1 Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.859621
Abstract: Objective To clarify the function and mechanisms of sevoflurane (Sev) on ferroptosis in glioma cells. Methods Different concentrations of Sev were used to treat glioma cells U87 and U251. Ferroptosis inducer Erastin was used to… read more here.
Keywords: chac1; u87 u251; glioma cells; u251 cells ... See more keywords
Pharmacological Inhibition of Membrane Signaling Mechanisms Reduces the Invasiveness of U87-MG and U251-MG Glioblastoma Cells In Vitro
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15041027
Abstract: Simple Summary Glioblastoma is a brain tumor that is among the deadliest of human cancers. The invasive spreading of the tumor cells allows subpopulations to escape chemo and radiation treatments and infiltrate other areas of… read more here.
Keywords: glioblastoma cells; cell; u87 u251; glioblastoma ... See more keywords
IMPDH Inhibition Decreases TERT Expression and Synergizes the Cytotoxic Effect of Chemotherapeutic Agents in Glioblastoma Cells
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms25115992
Abstract: IMP dehydrogenase (IMPDH) inhibition has emerged as a new target therapy for glioblastoma multiforme (GBM), which remains one of the most refractory tumors to date. TCGA analyses revealed distinct expression profiles of IMPDH isoenzymes in… read more here.
Keywords: u251 cells; u87 u251; impdh inhibition; expression ... See more keywords
Multiple Pathway-Dephosphorylated ASK-1 Confers Temozolomide-Resistance to Human Glioma Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Turkish neurosurgery"
DOI: 10.5137/1019-5149.jtn.41212-22.1
Abstract: AIM Temozolomide (TMZ) resistance contributes to the unfavorable prognosis of glioma, however, the mechanism of resistance is unknown. ASK-1 has various functions in many tumors, but its function in glioma is poorly understood. This study… read more here.
Keywords: u87 u251; tmz resistant; glioma cells; ask ... See more keywords
Ethyl pyruvate inhibits glioblastoma cells migration and invasion through modulation of NF-κB and ERK-mediated EMT
Sign Up to like & getrecommendations! Published in 2020 at "PeerJ"
DOI: 10.7717/peerj.9559
Abstract: Background Glioblastoma is a grade IV glioma with the highest degree of malignancy and extremely high incidence. Because of the poor therapeutic effect of surgery and radiochemotherapy, glioblastoma has a high recurrence rate and lethality,… read more here.
Keywords: invasion; erk; ethyl pyruvate; u87 u251 ... See more keywords