Articles with "ubc9 sumo" as a keyword



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The UBC9/SUMO pathway affects E-cadherin cleavage in HPV-positive head and neck cancer

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Published in 2022 at "Frontiers in Molecular Biosciences"

DOI: 10.3389/fmolb.2022.940449

Abstract: Functional loss of E-cadherin is frequent during tumor progression and occurs through a variety of mechanisms, including proteolytic cleavage. E-cadherin downregulation leads to the conversion of a more malignant phenotype promoting Epithelial to Mesenchymal Transition… read more here.

Keywords: ubc9 sumo; neck cancer; cleavage; head neck ... See more keywords