3-O-glycosylation of kaempferol restricts the supply of the benzenoid precursor of ubiquinone (Coenzyme Q) in Arabidopsis thaliana.
Sign Up to like & getrecommendations! Published in 2021 at "Phytochemistry"
DOI: 10.1016/j.phytochem.2021.112738
Abstract: Ubiquinone (Coenzyme Q) is a vital respiratory cofactor and antioxidant in eukaryotes. The recent discovery that kaempferol serves as a precursor for ubiquinone's benzenoid moiety both challenges the conventional view of flavonoids as specialized metabolites,… read more here.
Keywords: ubiquinone; arabidopsis thaliana; kaempferol; precursor ubiquinone ... See more keywords
The Newborn Fmr1 Knockout Mouse: A Novel Model of Excess Ubiquinone and Closed Mitochondrial Permeability Transition Pore in the Developing Heart
Sign Up to like & getrecommendations! Published in 2020 at "Pediatric research"
DOI: 10.1038/s41390-020-1064-6
Abstract: Background Mitochondrial permeability transition pore (mPTP) closure triggers cardiomyocyte differentiation during development while pathological opening causes cell death during myocardial ischemia-reperfusion and heart failure. Ubiquinone modulates the mPTP; however, little is known about its mechanistic… read more here.
Keywords: ubiquinone; heart; fmr1; newborn fmr1 ... See more keywords
The Modulation of Ubiquinone, a Lipid Antioxidant, on Neuronal Voltage-Gated Sodium Current
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14163393
Abstract: Ubiquinone, composed of a 1,4-benzoquinone and naturally produced in the body, actively participates in the mitochondrial redox reaction and functions as an endogenous lipid antioxidant, protecting against peroxidation in the pituitary-dependent hormonal system. However, the… read more here.
Keywords: voltage gated; lipid antioxidant; modulation ubiquinone; voltage ... See more keywords