Articles with "ubiquitin carboxyl" as a keyword



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Decreased UCHL1 expression as a cytologic biomarker for aggressive behavior in pancreatic neuroendocrine tumors

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Published in 2018 at "Surgery"

DOI: 10.1016/j.surg.2017.04.040

Abstract: Background. There are currently no reliable markers associated with aggressive behavior in well‐differentiated and moderately differentiated pancreatic neuroendocrine tumors. We aimed to determine whether expression of ubiquitin carboxyl‐terminal hydrolase L1 in conjunction with Ki67 can… read more here.

Keywords: aggressive behavior; pancreatic neuroendocrine; carboxyl terminal; ubiquitin carboxyl ... See more keywords
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Ubiquitin Carboxyl Terminal Hydrolase L1 Attenuates TNF-α-Mediated Vascular Smooth Muscle Cell Migration Through Suppression of NF-κB Activation.

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Published in 2018 at "International heart journal"

DOI: 10.1536/ihj.17-541

Abstract: Ubiquitin carboxyl terminal hydrolase L1 (UCH-L1) is one of the deubiquitinating enzymes in the ubiquitin-proteasome system. It has been shown that UCH-L1 could markedly decrease neointima formation through suppressing vascular smooth muscle cell (VSMC) proliferation… read more here.

Keywords: cell migration; carboxyl terminal; ubiquitin carboxyl; migration ... See more keywords
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Ubiquitin Carboxyl-Terminal Hydrolase L1 of Cardiomyocytes Promotes Macroautophagy and Proteostasis and Protects Against Post-myocardial Infarction Cardiac Remodeling and Heart Failure

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Published in 2022 at "Frontiers in Cardiovascular Medicine"

DOI: 10.3389/fcvm.2022.866901

Abstract: Ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) is a deubiquitinase known to play essential roles in the nervous tissue. Myocardial upregulation of UCHL1 was observed in human dilated cardiomyopathy and several animal models of heart disease, but… read more here.

Keywords: mice; terminal hydrolase; heart; ubiquitin carboxyl ... See more keywords