The role of ubiquitin-conjugating enzyme Ube2j1 phosphorylation and its degradation by proteasome during endoplasmic stress recovery
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cell Communication and Signaling"
DOI: 10.1007/s12079-017-0386-6
Abstract: The human Ube2j1 and Ube2j2 are the only ubiquitin-conjugating enzymes (E2s) that are localized to endoplasmic reticulum (ER) through its C-terminal transmembrane domains. Ube2j1 is a known substrate of MAPK signalling pathway and it is… read more here.
Keywords: recovery; ube2j1 phosphorylation; phosphorylated ube2j1; stress ... See more keywords
Ubiquitin conjugating enzyme E2 M promotes apoptosis in osteoarthritis chondrocytes via Wnt/β-catenin signaling.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.06.095
Abstract: In this study, the role of ubiquitin conjugating enzyme E2 M (UBE2M) and molecular mechanisms associated with osteoarthritis (OA) were explored. Cartilage tissues and corresponding healthy tissues from OA patients were isolated. Our data suggested… read more here.
Keywords: conjugating enzyme; catenin signaling; catenin; ubiquitin conjugating ... See more keywords
Computational Analysis of the Mechanism of the Ubiquitin Conjugating Enzyme Ubc13
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.1579
Abstract: case we examined the sodiumdependent glucose co-transporter of Vibrio parahaemolyticus (vSGLT) which mediates galactose transport into the cytoplasm of vibrio parahaemolyticus bacteria. According literature, kinetic of cotransporter has between 5 and 6 states or conformations,… read more here.
Keywords: analysis mechanism; conjugating enzyme; analysis; computational analysis ... See more keywords
Recombinant ubiquitin-conjugating enzyme of Eimeria maxima induces immunogenic maturation in chicken splenic-derived dendritic cells and drives Th1 polarization in-vitro.
Sign Up to like & getrecommendations! Published in 2020 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2020.104162
Abstract: Dendritic cells (DCs) are key linkages between innate immunity and acquired immunity. The antigens that promote the functions of DCs might be the effective candidates of novel vaccine. In this research, the ability of ubiquitin-conjugating… read more here.
Keywords: chsp dcs; dcs; conjugating enzyme; remuce ... See more keywords
African swine fever virus encodes for an E2-ubiquitin conjugating enzyme that is mono- and di-ubiquitinated and required for viral replication cycle
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-21872-2
Abstract: African swine fever virus is the etiological agent of a contagious and fatal acute haemorrhagic viral disease for which there are no vaccines or therapeutic options. The ASFV encodes for a putative E2 ubiquitin conjugating… read more here.
Keywords: swine fever; mono ubiquitinated; conjugating enzyme; african swine ... See more keywords
E2 ubiquitin-conjugating enzymes (UBCs): drivers of ubiquitin signalling in plants.
Sign Up to like & getrecommendations! Published in 2022 at "Essays in biochemistry"
DOI: 10.1042/ebc20210093
Abstract: Most research in the field of ubiquitination has focused on E3 ubiquitin ligases because they are the specificity determinants of the ubiquitination process. Nevertheless, E2s are responsible for the catalysis during ubiquitin transfer, and are… read more here.
Keywords: ubiquitin signalling; enzymes ubcs; ubcs drivers; drivers ubiquitin ... See more keywords
Knockdown of ubiquitin-conjugating enzyme E2T (UBE2T) suppresses lung adenocarcinoma progression via targeting fibulin-5 (FBLN5)
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2060162
Abstract: ABSTRACT Lung adenocarcinoma (LUAD) is the main histological type of lung cancer, which is the leading cause of cancer-related deaths. Accumulating evidence has displayed that UBE2T is related to tumor progression. However, its role in… read more here.
Keywords: lung adenocarcinoma; progression; conjugating enzyme; fbln5 ... See more keywords
Characterization and expression analysis of genes encoding ubiquitin conjugating domain-containing enzymes in Carica papaya
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0171357
Abstract: Background Ripening affects the quality and nutritional contents of fleshy fruits and is a crucial process of fruit development. Although several studies have suggested that ubiquitin-conjugating enzyme (E2s or UBC enzymes) are involved in the… read more here.
Keywords: fruit; analysis; carica papaya; ubiquitin conjugating ... See more keywords
Prevalence of antibodies targeting ubiquitin-conjugating enzyme 2L3 and eukaryote translation elongation factor 1 α1 in Chinese Han and American Caucasian populations with type 1 diabetes
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DOI: 10.1530/ec-22-0325
Abstract: We assessed the prevalence of two novel islet autoantibodies, those targeting ubiquitin-conjugating enzyme 2L3 (UBE2L3) and eukaryote translation elongation factor 1 α1 (eEF1A1), in type 1 diabetes mellitus (T1DM) to evaluate their utility in T1DM… read more here.
Keywords: american caucasian; targeting ubiquitin; prevalence; conjugating enzyme ... See more keywords
The UBE2D ubiquitin conjugating enzymes: Potential regulatory hubs in development, disease and evolution
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.1058751
Abstract: Ubiquitination of cellular proteins plays critical roles in key signalling pathways and in the regulation of protein turnover in eukaryotic cells. E2 ubiquitin conjugating enzymes function as essential intermediates in ubiquitination reactions by acting as… read more here.
Keywords: development; ube2d ubiquitin; conjugating enzymes; regulation ... See more keywords
African swine fever virus ubiquitin-conjugating enzyme pI215L inhibits IFN-I signaling pathway through STAT2 degradation
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1081035
Abstract: African swine fever virus (ASFV) is the causative agent of one of the most lethal diseases affecting domestic pig and wild boar, which is endangering the swine industry due to its rapid expansion. ASFV has… read more here.
Keywords: conjugating enzyme; stat2; ifn; ubiquitin conjugating ... See more keywords