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Published in 2023 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2023.1184934
Abstract: The attachment of ubiquitin to a substrate (ubiquitination or ubiquitylation) impacts its lifetime and regulates its function within the cell. Several classes of enzymes oversee the attachment of ubiquitin to the substrate: an E1 activating…
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Keywords:
mass spectrometry;
tof mass;
ubiquitin enzymes;
maldi tof ... See more keywords
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1
Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21176335
Abstract: Ubiquitination is a multi-step enzymatic process that involves the marking of a substrate protein by bonding a ubiquitin and protein for proteolytic degradation mainly via the ubiquitin–proteasome system (UPS). The process is regulated by three…
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Keywords:
ubiquitin enzymes;
effect dysfunctional;
enzymes pathogenesis;
common diseases ... See more keywords