Chronic over‐expression of ubiquitin impairs learning, reduces synaptic plasticity, and enhances GRIA receptor turnover in mice
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.14630
Abstract: Ubiquitin is an essential signaling protein that controls many different cellular processes. While cellular ubiquitin levels normally cycle between pools of free and conjugated ubiquitin, the balance of these ubiquitin pools can be shifted by… read more here.
Keywords: ubiquitin levels; expression; mice; synaptic plasticity ... See more keywords
Ubiquitin levels: the next target against gynecological cancers?
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Investigation"
DOI: 10.1172/jci98262
Abstract: Ubiquitylation is a tightly regulated process that is essential for appropriate cell survival and function, and the ubiquitin pathway has shown promise as a therapeutic target for several forms of cancer. In this issue of… read more here.
Keywords: levels next; gynecological cancers; target; ubiquitin levels ... See more keywords