Novel UCHL1 mutations reveal new insights into ubiquitin processing
Sign Up to like & getrecommendations! Published in 2017 at "Human Molecular Genetics"
DOI: 10.1093/hmg/ddw391
Abstract: Recessive loss of function of the neuronal ubiquitin hydrolase UCHL1 has been implicated in early-onset progressive neurodegeneration (MIM no. 615491), so far only in one family. In this study a second family is characterized, and… read more here.
Keywords: ubiquitin processing; reveal new; uchl1 mutations; activity ... See more keywords
Development of Ubiquitin Tools for Studies of Complex Ubiquitin Processing Protein Machines
Sign Up to like & getrecommendations! Published in 2020 at "Current Organic Chemistry"
DOI: 10.2174/1385272823666191113161511
Abstract: Ubiquitination is one of the most extensive post-translational modifications in eukaryotes and is involved in various physiological processes such as protein degradation, autophagy, protein interaction, and protein localization. The ubiquitin (Ub)-related protein machines include Ub-activating… read more here.
Keywords: protein; ubiquitin processing; processing protein; protein machines ... See more keywords