Analysis of ubiquitin signaling and chain topology cross-talk.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2020.103634
Abstract: Protein ubiquitination is a powerful post-translational modification implicated in many cellular processes. Although ubiquitination is associated with protein degradation, depending on the topology of polyubiquitin chains, protein ubiquitination is connected to non-degradative events in DNA… read more here.
Keywords: ubiquitin signaling; chain; chain topology; topology ... See more keywords
Towards a molecular basis of ubiquitin signaling: A dual-scale simulation study of ubiquitin dimers
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1006589
Abstract: Covalent modification of proteins by ubiquitin or ubiquitin chains is one of the most prevalent post-translational modifications in eukaryotes. Different types of ubiquitin chains are assumed to selectively signal respectively modified proteins for different fates.… read more here.
Keywords: basis ubiquitin; molecular basis; ubiquitin dimers; ubiquitin signaling ... See more keywords
Modulation of Ubiquitin Signaling in Innate Immune Response by Herpesviruses
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23010492
Abstract: The ubiquitin proteasome system (UPS) is a protein degradation machinery that is crucial for cellular homeostasis in eukaryotes. Therefore, it is not surprising that the UPS coordinates almost all host cellular processes, including host–pathogen interactions.… read more here.
Keywords: modulation ubiquitin; immune response; innate immune; ubiquitin signaling ... See more keywords
The termination of UHRF1-dependent PAF15 ubiquitin signaling is regulated by USP7 and ATAD5
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.79013
Abstract: UHRF1-dependent ubiquitin signaling plays an integral role in the regulation of maintenance DNA methylation. UHRF1 catalyzes transient dual mono-ubiquitylation of PAF15 (PAF15Ub2), which regulates the localization and activation of DNMT1 at DNA methylation sites during… read more here.
Keywords: paf15; dna methylation; ubiquitin signaling; termination ... See more keywords