Articles with "ubiquitin threshold" as a keyword



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CMG helicase disassembly is controlled by replication fork DNA, replisome components and a ubiquitin threshold

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Published in 2020 at "eLife"

DOI: 10.7554/elife.60371

Abstract: The eukaryotic replisome assembles around the CMG helicase, which stably associates with DNA replication forks throughout elongation. When replication terminates, CMG is ubiquitylated on its Mcm7 subunit and disassembled by the Cdc48/p97 ATPase. Until now,… read more here.

Keywords: dna; ubiquitin threshold; replication; cmg helicase ... See more keywords