Regulation of cargo transfer between ESCRT-0 and ESCRT-I complexes by flotillin-1 during endosomal sorting of ubiquitinated cargo
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DOI: 10.1038/oncsis.2017.47
Abstract: Ubiquitin-dependent sorting of membrane proteins in endosomes directs them to lysosomal degradation. In the case of receptors such as the epidermal growth factor receptor (EGFR), lysosomal degradation is important for the regulation of downstream signalling.… read more here.
Keywords: endosomal sorting; escrt; ubiquitinated cargo; escrt complexes ... See more keywords