Quantitative Assessment of Arsenite-Induced Perturbation of Ubiquitinated Proteome.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.2c00197
Abstract: Arsenic contamination in food and groundwater constitutes a public health concern for more than 200 million people worldwide. Individuals chronically exposed to arsenic through drinking and ingestion exhibit a higher risk of developing cancers and… read more here.
Keywords: arsenite induced; ubiquitinated proteome; ubiquitination; arsenite exposure ... See more keywords
Rewiring of the ubiquitinated proteome determines ageing in C. elegans
Sign Up to like & getrecommendations! Published in 2021 at "Nature"
DOI: 10.1038/s41586-021-03781-z
Abstract: Ageing is driven by a loss of cellular integrity1. Given the major role of ubiquitin modifications in cell function2, here we assess the link between ubiquitination and ageing by quantifying whole-proteome ubiquitin signatures in Caenorhabditis… read more here.
Keywords: degradation; longevity; determines ageing; proteome determines ... See more keywords