Site-specific ubiquitination of MLKL targets it to endosomes and targets Listeria and Yersinia to the lysosomes
Sign Up to like & getrecommendations! Published in 2022 at "Cell Death and Differentiation"
DOI: 10.1038/s41418-021-00924-7
Abstract: Phosphorylation of the pseudokinase mixed lineage kinase domain-like protein (MLKL) by the protein kinase RIPK3 targets MLKL to the cell membrane, where it triggers necroptotic cell death. We report that conjugation of K63-linked polyubiquitin chains… read more here.
Keywords: site specific; ubiquitination mlkl; cell death; mlkl ... See more keywords