SDCBP‐AS1 destabilizes β‐catenin by regulating ubiquitination and SUMOylation of hnRNP K to suppress gastric tumorigenicity and metastasis
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Communications"
DOI: 10.1002/cac2.12367
Abstract: Gastric cancer (GC) is among the most malignant tumors, yet the pathogenesis is not fully understood, especially the lack of detailed information about the mechanisms underlying long non‐coding RNA (lncRNA)‐mediated post‐translational modifications. Here, the molecular… read more here.
Keywords: sdcbp as1; regulating ubiquitination; catenin regulating; ubiquitination sumoylation ... See more keywords
Histone H4 LRS mutations can attenuate UV mutagenesis without affecting PCNA ubiquitination or sumoylation.
Sign Up to like & getrecommendations! Published in 2020 at "DNA repair"
DOI: 10.1016/j.dnarep.2020.102959
Abstract: UV is a significant environmental agent that damages DNA. Translesion synthesis (TLS) is a DNA damage tolerance pathway that utilizes specialized DNA polymerases to replicate through the damaged DNA, often leading to mutagenesis. In eukaryotic… read more here.
Keywords: dna; tls; ubiquitination sumoylation; histone ... See more keywords
Regulation of Glucose, Fatty Acid and Amino Acid Metabolism by Ubiquitination and SUMOylation for Cancer Progression
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DOI: 10.3389/fcell.2022.849625
Abstract: Ubiquitination and SUMOylation, which are posttranslational modifications, play prominent roles in regulating both protein expression and function in cells, as well as various cellular signal transduction pathways. Metabolic reprogramming often occurs in various diseases, especially… read more here.
Keywords: metabolism; sumoylation; ubiquitination sumoylation; amino acid ... See more keywords
Insights in Post-Translational Modifications: Ubiquitin and SUMO
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DOI: 10.3390/ijms23063281
Abstract: Both ubiquitination and SUMOylation are dynamic post-translational modifications that regulate thousands of target proteins to control virtually every cellular process. Unfortunately, the detailed mechanisms of how all these cellular processes are regulated by both modifications… read more here.
Keywords: modifications ubiquitin; insights post; translational modifications; post translational ... See more keywords
The Involvement of Ubiquitination and SUMOylation in Retroviruses Infection and Latency
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15040985
Abstract: Retroviruses, especially the pathogenic human immunodeficiency virus type 1 (HIV-1), have severely threatened human health for decades. Retroviruses can form stable latent reservoirs via retroviral DNA integration into the host genome, and then be temporarily… read more here.
Keywords: infection latency; infection; ubiquitination sumoylation;